Background: Day-case surgery, theatre direct admissions and elective surgery have revolutionised the surgical patient's pathway, and have minimised the length of their hospital stay. However, with large numbers of medical students placed mostly at teaching hospitals, this has also significantly reduced students' exposure to clinical signs in surgery. This study aimed to assess whether the preoperative assessment clinic would be an appropriate teaching arena to offer medical students exposure to clinical signs.
Methods: Junior doctors assigned to the preoperative assessment clinic were asked to fill out a specially designed questionnaire for each patient they reviewed. This included the planned operation, presenting complaint, and identification and categorisation of objective clinical signs on examination. The assessor was asked whether the patient was suitable for, and amenable to, having medical students observe. The presenting complaints and clinical signs were referenced to the curriculum for Oxford University's second Bachelor of Medicine examinations (finals).
Results: Of the 100 patients seen in 40 clinics, only four refused to be seen by a medical student. Of the remaining patients, 89 (92%) had presenting complaints listed on the core curriculum for Oxford University. Seventy-six (79%) patients had objective clinical signs on examination. Only three patients (3%) had neither clinical signs nor core relevant presenting complaints.
Conclusions: The results clearly demonstrate that preoperative assessment is an arena that would give medical students two important opportunities: to examine objective clinical signs and to take histories of presenting complaints from the core curriculum. This learning opportunity would otherwise be missed.
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http://dx.doi.org/10.1111/j.1743-498X.2011.00443.x | DOI Listing |
JAMA Netw Open
January 2025
Coronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Importance: Multisystem inflammatory syndrome in children (MIS-C) is an uncommon but severe hyperinflammatory illness that occurs 2 to 6 weeks after SARS-CoV-2 infection. Presentation overlaps with other conditions, and risk factors for severity differ by patient. Characterizing patterns of MIS-C presentation can guide efforts to reduce misclassification, categorize phenotypes, and identify patients at risk for severe outcomes.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Laboratory of NeuroImaging, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.
Importance: Cannabis use has increased globally, but its effects on brain function are not fully known, highlighting the need to better determine recent and long-term brain activation outcomes of cannabis use.
Objective: To examine the association of lifetime history of heavy cannabis use and recent cannabis use with brain activation across a range of brain functions in a large sample of young adults in the US.
Design, Setting, And Participants: This cross-sectional study used data (2017 release) from the Human Connectome Project (collected between August 2012 and 2015).
Asian Pac J Cancer Prev
January 2025
D1 S.P. Botkin City Clinical Hospital, Moscow, Russia.
Objectives: To study the predictive role of tumor-associated neutrophils in early luminal HER2-negative breast cancer.
Materials And Methods: This is a retrospective study conducted on 60 women cases aged from 31 to 79 years underwent surgery for luminal HER2-negative ductal breast cancer in tertiary care cancer centre. We first estimated basic morphological signs: tumor size, tumor grade (by Nottingham Histologic Score), tumor infiltrating lymphocytes (TILs), Lymphovascular invasion, hormonal receptors status, proliferative index, and regional lymph nodes metastasis.
Intern Emerg Med
January 2025
Unit of Internal Medicine and Clinical Oncology "G. Baccelli", Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari Aldo Moro Medical School, Bari, Italy.
Inborn errors of immunity (IEI) entail a diverse group of disorders resulting from hereditary or de novo mutations in single genes, leading to immune dysregulation. This study explores the clinical utility of next-generation sequencing (NGS) techniques in diagnosing monogenic immune defects. Eight patients attending the immunodeficiency clinic and with unclassified antibody deficiency were included in the analysis.
View Article and Find Full Text PDFFASEB J
January 2025
Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
With the emergence of high-quality sequencing technologies, further research on transcriptomes has become possible. Circular RNA (circRNA), a novel type of endogenous RNA molecule with a covalently closed circular structure through "back-splicing," is reported to be widely present in eukaryotic cells and participates mainly in regulating gene and protein expression in various ways. It is becoming a research hotspot in the non-coding RNA field.
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