Aim: This retrospective analysis presents our experience in treating Fournier gangrene (FG) and aims to bring in focus diagnostic and therapeutic problems as well as early and aggressive treatment.
Patients And Methods: A total of 16 male patients were included in the study. The gastrointestinal form was seen in 5 and the urogenital form in 11 patients. The subjects ranged in age from 39 to 74 years (average 61) for the urogenital, and from 48 to 72 (average 58) for the gastrointestinal form. Other conditions were seen in 9 patients (diabetes mellitus was most common). Most patients were infected with several bacteria. We performed colostomy in 1 patient, orchidectomy in 2 patients, cystostomy in 2 patients and penis amputation in 1 patient. Ultrasound-guided biopsy or aspiration, and CT was also used. Aggressive surgical necrectomy and aggressive antimicrobial therapy was used.
Results: Treatment was successful in 14 of 16 patients (87.5%). The length of hospitalization was 19-58 days (average 48) for the urogenital form and 24-56 days (average 41) for the gastrointestinal form. Mortality was 12.5%. A lethal outcome was recorded in two patients infected with methicillin-resistant Staphylococcus aureus. The average time between onset and hospitalization was 3-11 days (5 on average) for urogenital FG and 4-10 days (average 6) for gastrointestinal FG. Treatment was significantly longer in patients with a comorbidity, such as diabetes or liver cirrhosis due to alcohol abuse.
Conclusion: Early diagnosis as well as intensive and aggressive treatment are key to successful treatment of FG. Comorbidity increases length of therapy and lowers the chance for recovery. Disease can be seen again several years after the initial outburst.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000327510 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Colic in infants is defined as excessive crying in an otherwise healthy and thriving baby. Colic is a common but poorly understood and often frustrating problem for caregivers.
Objective: To study whether osteopathic treatments of infants with infantile colic / excessive crying (IC/EC) have an impact on the subjectively perceived psychological stress of caregivers compared to usual care.
Cholangioscope-Assisted Endoscopic Retrograde Appendicitis Therapy in the Management of Chronic Abdominal Pain Related to the Appendix: A Single-Center Retrospective Study.
Dig Dis Sci
January 2025
Infectious Diseases Department, Suining Central Hospital, Suining, Sichuan, China.
Background: The diagnosis and treatment of chronic abdominal pain related to the appendix have always been challenging. In the past, an appendectomy was the main approach for suspected chronic abdominal pain related to the appendix, but there was an associated risk of negative appendectomy. In recent years, cholangioscope-assisted endoscopic retrograde appendicitis therapy (ERAT) has been used to view the appendiceal cavity directly for flushing, stone removal, biopsy, and other operations, thereby achieving precise treatment.
View Article and Find Full Text PDFSclerotherapy with low-dose 5% ethanolamine oleate in oral vascular anomalies: a retrospective study.
Oral Surg Oral Med Oral Pathol Oral Radiol
January 2025
Diagnostic Center for Oral Diseases, School of Dentistry, Universidade Federal de Pelotas, Rio Grande do Sul, Brazil. Electronic address:
Objective: To describe the characteristics and outcomes of a cohort of patients with oral vascular anomalies (OVA) treated with sclerotherapy using 5% ethanolamine oleate at a dosage of 0.1 mL per 10 mm of lesion size.
Study Design: Sixty-seven patients were selected from a review of 300 medical records of individuals who had been diagnosed with OVA.
Carotid disease treatment modality and its association with post-operative vasoactive medication utilization and hospital length of stay.
J Vasc Surg
January 2025
Southern California Permanente Medical Group, Kaiser Permanente,; University of California, Riverside School of Medicine.
Objective: Carotid artery disease is a major cause of stroke for which the standard treatment has traditionally been a combination of medical management and intervention, including both carotid endarterectomy (CEA) and transfemoral carotid artery stenting (TF-CAS). In recent years, transcarotid artery revascularization (TCAR) has been adopted as a promising treatment following FDA approval in 2015. In terms of stroke reduction, TCAR has been found to have equivalent outcomes with CEA with shorter operative times.
View Article and Find Full Text PDFAssociation Between Daily Insulin Dose Adjustments and Glycemic Control in Non-Critically Ill Hospitalized Hyperglycemic Patients: A Retrospective Cohort Study.
Endocr Pract
January 2025
Division of Endocrinology, Diabetes, & Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:
Objective: To evaluate the efficacy of daily insulin dose increases in managing inpatient hyperglycemia.
Methods: Retrospective study of patients discharged from two urban academic medical centers and three large suburban community hospitals between 2015 and 2019 who received ≥10 units of basal insulin on any day. On hyperglycemic days (mean glucose ≥180 mg/dL), we categorized the relative insulin dose increases into four categories based on percentage changes from the previous day.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!