Unlabelled: Medication errors occur very frequently. The limited knowledge of contributing factors and risks prevents the development and testing of successful preventive strategies.
Objective: To investigate the differences between the ordered and dispensed drugs, and to identify the risks during medication.
Methods: Prospective direct observation at two inpatient hospital wards.
Results: The number of observed doses was 775 and the number of ordered doses was 806. It was found that from the total opportunities of 803 errors 114 errors occurred in dispensed drugs corresponding to an error rate of 14.1%. Among the different types of errors, the most important errors were: dispensing inappropriate doses (25.4%), unauthorized tablet halving or crushing (24.6%), omission errors (16.4%) and dispensing an active ingredient different from the ordered (14.2%). 87% of drug dispensing errors were considered as errors with minor consequences, while 13% of errors were potentially serious.
Conclusions: Direct observation of the drug dispensing procedure appears to be an appropriate method to observe errors in medication of hospital wards. The results of the study and the identified risks are worth to be reconsidered and prevention measures should be applied to everyday health care practice to improve patient safety.
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http://dx.doi.org/10.1556/OH.2011.29198 | DOI Listing |
Alzheimers Dement
December 2024
The George Institute for Global Health, University of New South Wales, Imperial College London, Sydney, NSW, Australia.
Background: Recent growth in the functionality and use of technology has prompted an increased interest in the potential for remote or decentralised clinical trials in dementia. There are many potential benefits associated with decentralised medication trials, but the field is currently lacking specific recommendations for their delivery in the dementia field.
Method: A modified Delphi method engaged a panel with substantial expertise in dementia trial design and delivery and backgrounds that included neurology, psychiatry, pharmacology and psychology, to develop recommendations for the conduct of decentralised medication trials in dementia prevention.
Mikrochim Acta
January 2025
Tyndall National Institute, University College Cork, Lee Maltings Complex, Dyke Parade, Cork, T12R5CP, Ireland.
Therapeutic and misuse of veterinary drugs, such as antibiotics, can increase the potential risk of residue contamination in animal-derived food products. For milk, these residual antibiotics can have an impact on efficiency in dairy processing factories, as well as economic loss, and can also cause side effects on consumer health. Lateral flow immunoassays (LFIAs) are gaining popularity for their ease of use, low cost and their fulfilment to the REASSURED (real-time connection/monitoring, easy sampling, affordable, specific, user-friendly, rapid/robust, equipment free, deliverable to end user) criteria.
View Article and Find Full Text PDFPharmacoepidemiol Drug Saf
January 2025
School of Population Health, RCSI University of Medicine and Health Sciences, Dublin 2, Ireland.
Background: Drug-drug interactions (DDIs), highly prevalent amongst the elderly, can lead to avoidable medication-related harm. Cardiovascular and central nervous system (CNS) drugs are commonly implicated. To date, there is no consensus on how to measure DDIs, making comparisons across countries challenging.
View Article and Find Full Text PDFPharmacoepidemiol Drug Saf
January 2025
Pharmacy and Pharmacology Center, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Purpose: Studies on antihypertensive treatment are important, as hypertension remains the major risk factor for cardiovascular morbidity and premature death. However, antihypertensive medicines are also used for other conditions, and the use of these medicines as a proxy for a diagnosis of hypertension might lead to misclassification in pharmacoepidemiological studies. This study aimed to investigate to what extent people dispensed antihypertensive medicines have been diagnosed with hypertension.
View Article and Find Full Text PDFRheumatology (Oxford)
January 2025
Clinical Epidemiology Division, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital T2, Stockholm, Sweden.
Objectives: Systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) are more common in women, partly due to differences in female sex hormones. Menopausal hormone therapy (MHT) is widely used to alleviate climacteric symptoms. Here, the relationship between MHT and SLE/SSc was investigated in a nested case-control study.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!