Malakoplakia of the prostate is a rarely reported granulomatous inflammatory disorder which may clinically mimic carcinoma of the prostate gland. This paper reported 1 case of malakoplakia of the prostate which was successfully diagnosed with the use of transrectral ultrasound and ultrasound-guided needle biopsy, and the cases and related articles were reviewed. The patient was successfully cured by the use of compound sulfamethoxazole tablet (SMZ-TMP) at the same time. Histologic examination is required to make the correct diagnosis. Biopsy of the prostate and antibiotics should be used clinically.
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