[Gender-related differences in pathological characteristics of upper urinary tract urothelial carcinoma: analysis of 597 cases].

Objective: To assess the sex differences in pathologic characteristics of Chinese patients with upper urinary tract urothelial carcinoma (UUTUC).

Methods: Between January 2004 and December 2010, 597 patients (253 men and 344 women) underwent surgical management at Peking University First Hospital for pathologically proven UUTUC. We reviewed pathological data from these patients, and used univariate analysis to determine sex differences.

Results: Of the 597 consecutive cases, mean age was 67 years ranging from 20 to 94 years. Univariate analyses showed that female patients had less proportion of large tumor (P=0.017), local advanced tumor (P<0.001) and lymph node metastasis (P=0.022). No significant sex-related differences were found in the age, tumor grade, and tumor number.

Conclusion: In Chinese UUTUC patients, female patients were more common. Females are less likely to have more advanced pathologic stage than males.