AI Article Synopsis

  • A 23-year-old man presented unconscious with low oxygen levels (hypoxemia) and was diagnosed with biventricular non-compaction cardiomyopathy, showing structural heart defects (VSD and ASD).
  • Doppler echocardiography indicated abnormal blood flow patterns: a left-to-right shunt through the ventricular septal defect and a right-to-left shunt through the atrial septal defect.
  • Cardiac catheterization showed high pressure in the right atrium but normal pulmonary pressure, suggesting that the right-to-left shunt from the ASD contributed to his hypoxemia primarily due to right ventricular dysfunction, rather than pulmonary hypertension.

Article Abstract

Echocardiography and magnetic resonance imaging revealed biventricular non-compaction cardiomyopathy with ventricular (VSD) and atrial (ASD) septal defects in an unconscious, 23-year-old hypoxemic man. Doppler echocardiography showed a left-to-right shunt across the VSD and a right-to-left shunt across the ASD. Cardiac catheterization revealed elevated right atrial pressure, although pulmonary pressure was normal. We considered that the atrial right-to-left shunt had induced the hypoxemia, which was related mainly to right ventricular dysfunction in this biventricular non-compaction cardiomyopathy, but it was not related to pulmonary hypertension.

Download full-text PDF

Source
http://dx.doi.org/10.2169/internalmedicine.50.5290DOI Listing

Publication Analysis

Top Keywords

right-to-left shunt
12
biventricular non-compaction
12
non-compaction cardiomyopathy
12
atrial right-to-left
8
pulmonary hypertension
8
septal defects
8
atrial
5
shunt
4
shunt pulmonary
4
hypertension patient
4

Similar Publications

Background: Superior caval vein obstruction is a rare complication of endocardial pacing lead implantation that can result in a right to left shunt.

Case Summary: A 3-year-old child with type 2 Brugada syndrome presented with mild cyanosis post-endocardial pacing implantation due to evolutionary right superior caval vein obstruction. This obstruction resulted in a right to left shunt across a previously unrecognized patent levo-atrial cardinal vein associated with partial anomalous pulmonary venous drainage.

View Article and Find Full Text PDF

Patent foramen ovale: A variant of normal or a true congenital heart disease?

Cardiovasc Pathol

January 2025

Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua Medical School, Padova, Italy. Electronic address:

Foramen ovale plays a key role in foetal circulation, however it may remain patent after birth throughout the life. Its patency is so frequent in healthy people (27-35 %), such as to be considered a variant of normal. It is at risk of complications, like paradoxical embolism by right to left shunt with stroke, migraine, temporary blindness, as well as aneurysm, thrombosis and endocarditis of the fossa ovalis.

View Article and Find Full Text PDF

Hepatopulmonary syndrome (HPS), defined by the presence of pulmonary vascular dilatations that cause right-to-left transpulmonary shunting of venous blood with a consequential increase in the alveolar-arterial oxygen gradient, is a relatively frequent complication of chronic liver disease. While orthotopic liver transplantation (OLT) is indicated and often curative in HPS patients with end-stage liver disease (ESLD), little is known about the peri- and post-operative-period risks of CVA in OLT recipients with HPS. : We report a case series of five non-consecutive OLT recipients with HPS who developed ischemic and/or hemorrhagic CVAs during or shortly after OLT, raising concern that the risks of neurological complications remain increased even after OLT.

View Article and Find Full Text PDF

Role of narrow band imaging in assessing bronchial mucosal hypervascularization in COVID-19 patients.

Respir Med Res

January 2025

Pneumology Department, University Hospital Centre Amiens-Picardie, Amiens, France; AGIR Unit, University Picardie Jules Vernes, Amiens, France.

Background: SARS-CoV-2 virus which targets the lung vasculature is supposed to affect both pulmonary and bronchial arteries. This study evaluated the tracheobronchial vascularization density observed with narrow band imaging (NBI) in patients hospitalized for COVID-19 pneumonia. To determine if the observed changes were specific of COVID-19 patients, the procedure was also performed in non-COVID-19 patients.

View Article and Find Full Text PDF

Iatrogenic diversion of inferior vena cava to the left atrium presented as persistent hypoxemia: Case series.

Medicine (Baltimore)

January 2025

Department of Center for Pulmonary Vascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Rationale: The transcatheter closure and atrioseptopexy are the main treatment methods for atrial septal defect (ASD). However, persistent hypoxemia due to iatrogenic diversion of inferior vena cava (IVC) to the left atrium (LA) is reported as a rare complication after ASD closure. Contrast echocardiology is a reliable and powerful tool to detect iatrogenic diversion and identify the etiology accurately.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!