AI Article Synopsis
- The use of subanesthetic doses of ketamine shows promise in treating complex pain syndromes that don't respond well to high doses of opioids, based on case reports and small studies.
- The case series discussed illustrates successful treatment outcomes for severe pain of various origins with intravenous ketamine.
- Further research is needed to determine the best dosing, treatment duration, and maintenance strategies for using ketamine in pain management.
Article Abstract
The benefits of ketamine in reducing pain are largely based on case reports and small clinical trials. We present a case series describing the application and efficacy of subanesthetic doses of ketamine in the treatment of complex pain syndromes poorly responsive to escalating doses of opioids. The discussion that follows suggests that subanesthetic intravenous ketamine can be used to successfully treat severe pain of different etiologies refractory to opioid dose escalation. Optimal dosing titration, duration of initial treatment, and the role of maintenance ketamine need to be further elucidated. Our case series adds to the extant literature supporting the role of subanesthetic ketamine for refractory pain problems.
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| http://dx.doi.org/10.1089/jpm.2010.0424 | DOI Listing |
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