With increasing environmental concerns, the need for environmentally friendly organic synthesis has gained increased importance. In this regard, bismuth(III) compounds are especially attractive as "green" reagents and catalysts for organic synthesis. Bismuth(III) compounds are remarkably nontoxic, relatively air and moisture stable, and easy to handle. The contributions from our laboratory in the last 5 years in the field of applications of bismuth(III) compounds as catalysts are presented.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/128_2011_194 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Establishing Composition of Solid Solution Based on Single Crystal and Powder X-ray Measurement: The Case of Halogenated Bismuth(III) Complexes with Acetophenone-4-methyl-3-thiosemicarbazone.
Int J Mol Sci
October 2024
Faculty of Chemistry, Adam Mickiewicz University, 61-614 Poznań, Poland.
New bismuth (III) complexes with acetophenone-4-methyl-3-thiosemicarbazone (L) and halogens (Cl and Br) in both bridging and terminal positions have been synthesized and structurally characterized using single-crystal X-ray diffraction. The pure complexes (Cl or Br) were found to be highly isostructural, which motivated our attempts to create solid solutions of these complexes. A series of such compounds was prepared using various procedures and stoichiometries.
View Article and Find Full Text PDFFluorine-18 incorporation and radiometal coordination in macropa ligands for PET imaging and targeted alpha therapy.
Chem Commun (Camb)
October 2024
Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY-14853, USA.
Article Synopsis
- The development of theranostic agents using alpha emitters addresses a significant clinical need, focusing on combining therapeutic and diagnostic functions in medicine.* -
- A new ligand, macropa-F, was created to effectively bind to alpha therapeutic radiometals, and its properties were tested with lead-203 and bismuth-207 as substitutes for actual alpha-emitting isotopes.* -
- The resulting fluorine-18 and radiometal complexes demonstrated high stability in human serum for several days, showcasing a promising approach for theranostic applications in medicine.*
Mechanistic insights into bismuth(iii) inhibition of SARS-CoV-2 helicase.
Chem Sci
July 2024
Department of Chemistry and CAS-HKU Joint Laboratory of Metallomics on Heath and Environment, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China
The COVID-19 pandemic caused by SARS-CoV-2 resulted in a global public health crisis. In addition to vaccines, the development of effective therapy is highly desirable. Targeting a protein that plays a critical role in virus replication may allow pan-spectrum antiviral drugs to be developed.
View Article and Find Full Text PDFIs bismuth(III) able to inhibit the activity of urease? Puzzling results in the quest for soluble urease complexes for agrochemical and medicinal applications.
Dalton Trans
June 2024
Department of Chemistry "G. Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy.
Bismuth(III) complexes have been reported to act as inhibitors of the enzyme urease, ubiquitously present in soils and implicated in the pathogenesis of several microorganisms. The general insolubility of Bi(III) complexes in water at neutral pH, however, is an obstacle to their utilization. In our quest to improve the solubility of Bi(III) complexes, we selected a compound reported to inhibit urease, namely [Bi(HEDTA)]·2HO, and co-crystallized it with (i) racemic DL-histidine to obtain the conglomerate [Bi(HEDTA)(μ-D-His)]·6HO + [Bi(HEDTA)(μ-L-His)]·6HO, (ii) enantiopure L-histidine to yield [Bi(HEDTA)(μ-L-His)]·6HO, and (iii) cytosine to obtain [Bi(HEDTA)]·Cyt·2HO.
View Article and Find Full Text PDFCoordination environment dependence of anticancer activity in cyclometalated bismuth(III) complexes with C,O-chelating ligands.
J Inorg Biochem
July 2024
School of Medicine, Hunan University of Chinese Medicine, Changsha 410208, PR China. Electronic address:
In this paper, a series of cyclometalated bismuth(III) complexes bearing C,O-bidentate ligands were synthesized and characterized by techniques such as UV-vis, NMR, HRMS, and single crystal X-ray diffraction. Meanwhile, their cytotoxicities against various human cell lines, including colon cancer cells (HCT-116), breast cancer cells (MDA-MB-231), lung cancer cells (A549), gastric cancer cells (SGC-7901), and normal embryonic kidney cells (HEK-293) were assessed in vitro. Compared with the clinical cisplatin, most of the synthesized complexes possessed significantly higher degrees of anticancer activity and selectivity, giving a selectivity index of up to 71.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!