Background: There is evidence for an association between Modic type 1 and pain in patients with low back pain (LBP), but little knowledge about its effect on clinical outcomes.

Purpose: (1) To assess the prevalence of Modic changes, (2) to determine if Modic changes influence the clinical course of LBP, and (3) to identify prognostic factors for recovery.

Study Design/setting: Prospective clinical cohort study, with a 1-year follow-up. The treatment consisted of brief intervention and instruction in stretching. PATIENT'S SAMPLE: Two hundred and sixty-nine patients with chronic low back pain.

Outcome Measures: Socio-demographic variables, education, profession, self-reported measures, degenerative changes on MRI.

Methods: Linear growth model and Cox regression analysis.

Results: Five percent had a normal MRI, 14 and 50% had Modic 1 and Modic 2 changes. Modic changes were not significant covariates for the clinical course of pain, function or fear avoidance beliefs. Education was a strong prognostic factor for recovery.

Conclusions: Modic changes did not influence the clinical course of back pain and were not prognostic factors for recovery. Education was strongly associated with recovery.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296852PMC
http://dx.doi.org/10.1007/s00586-011-1964-6DOI Listing

Publication Analysis

Top Keywords

modic changes
24
clinical course
12
modic
8
changes influence
8
influence clinical
8
prognostic factors
8
course pain
8
changes
6
clinical
5
prognostic
4

Similar Publications

Morphological Patterns of Spinal Degeneration and Trauma in a Nigerian Population: a Retrospective Radio-Anatomic Study.

World Neurosurg

January 2025

Department of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, South Africa. Electronic address:

Background: Understanding the morphological patterns of degenerative and traumatic spinal conditions is essential for precise diagnosis and management plans. This study evaluates the sequence of structural changes in degenerative spinal disorder patients' disco-vertebral unit and the traumatic spinal injury patterns in a northwestern Nigerian population.

Methods: A hospital-based retrospective study reviewed radiologic images of 307 patients with spinal degeneration (n=269) and trauma (n=38) at two tertiary hospitals in Northwest Nigeria.

View Article and Find Full Text PDF

Pear-Shaped Disc as a Risk Factor for Postoperative Sclerotic Modic Changes After Transforaminal Lumbar Interbody Fusion.

Orthop Surg

January 2025

Department of Orthopaedic, Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Objective: Pear-shaped disc could increase the risk of intraoperative end-plate injury, which may lead to postoperative sclerotic Modic Changes (MCs). However, there are no studies on the relationship between pear-shaped disc and postoperative sclerotic MCs. Therefore, this study investigates the risk factors for postoperative sclerotic MCs following transforaminal lumbar interbody fusion (TLIF).

View Article and Find Full Text PDF

Purpose: To examine associations between lumbar intervertebral disc degeneration (LDD) and type II Modic changes (MC) when retaining information at each interspace ("interspace-level analysis"), as compared to aggregating information across interspaces as is typically done in spine research ("person-level analysis") . The study compared results from (1) interspace-level analyses assuming a common relationship across interspaces (the "interspace-level, common-relationship" approach), (2) interspace-level analyses allowing for interspace-specific associations (an "interspace-level, interspace-specific" approach), and (3) a conventional person-level analytic approach.

Methods: Adults in primary care (n=147) received lumbar spine magnetic resonance imaging (MRI) and neuroradiologist-evaluated assessments of prevalent disc height narrowing (DHN), type II MC, and other LDD parameters.

View Article and Find Full Text PDF
Article Synopsis
  • Vertebrogenic pain, often linked to damage in vertebral endplates, is transmitted through the basivertebral nerve (BVN) and is associated with Modic changes visible on MRI.
  • A five-year follow-up of three clinical trials assessing intraosseous radiofrequency ablation (BVNA) shows significant pain and functional improvement in patients with chronic low back pain.
  • Out of 320 participants, 249 (78%) completed the study, revealing major reductions in pain scores and enhancements in disability index, demonstrating BVNA as an effective treatment option.
View Article and Find Full Text PDF

Purpose: This study aims to investigate how aspirin influences lumbar degeneration by analyzing the effect of aspirin on patients with low back pain (LBP) and concurrent atherosclerosis.

Methods: Using 1:1 nearest neighbor matching based on propensity score matching (PSM), 73 patients who regularly took aspirin were assigned to the aspirin group, while another 73 patients who did not take aspirin formed the control group. Radiographs were used to measure lumbar lordosis (LL) and intervertebral height index (IHI).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!