The title compound, C(15)H(23)N(2)S(+)·Cl(-)·0.5H(2)O, was prepared from (6aS,11aR,11cS)-2,3,5,6,6a,7,11,11a,11b,11c-deca-hydro-3a,7a-diaza-1H,4H-benzo[de]anthracene-8-one (sophocarpine) and Lawesson's reagent. The thione-substituted ring is in an envelope conformation and the three other six-membered rings are in chair conformations. In the crystal, anions and cations are linked by N-H⋯Cl and weak C-H⋯Cl hydrogen bonds. One 0.5-occupancy solvent water mol-ecule lies on a twofold rotation axis and another 0.25-occupancy solvent water mol-ecule is in a general position. The H atoms of these water mol-ecules were not located or included in the refinement.
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http://dx.doi.org/10.1107/S160053681100972X | DOI Listing |
Assay Drug Dev Technol
January 2025
Institute of Pharmaceutical Research, GLA University, Mathura, India.
Folia Microbiol (Praha)
January 2025
Biofuels Institute, School of Emergency Management, School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, China.
Ginsenoside Rh2(S) is well-known for its therapeutic potential against diverse conditions, including some cancers, inflammation, and diabetes. The enzymatic activity of uridine diphosphate glycosyltransferase 51 (UGT51) from Saccharomyces cerevisiae plays a pivotal role in the glycosylation process between UDP-glucose (donor) and protopanaxadiol (acceptor), to form ginsenoside Rh2. However, the catalytic efficiency of the UGT51 has remained a challenging task.
View Article and Find Full Text PDFCurr Res Food Sci
December 2024
Department of Food Science and Technology, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran.
This study evaluated the effects of chemical modification, including ethanol, acetic acid, and natural deep eutectic solvents (NADES), on the secondary and tertiary structures, hydrophobicity, free amine content, protein-protein interactions, and functional properties of zein. The NADES used included choline chloride: oxalic acid, choline chloride: urea, choline chloride: glycerol, and glucose: citric acid. The results reveal that the NADES system significantly altered zein's structures, as evidenced by Fourier transform infrared spectroscopy, fluorescence, and Ultraviolet-Visible Spectroscopy analysis.
View Article and Find Full Text PDFUnderstanding how vitamins and fertilizers interact in aquatic environments is crucial for managing water quality, protecting aquatic life, and promoting sustainable agricultural practices. The molecular interactions between nicotinamide (NA) and two fertilizers, potassium chloride (KCl) and diammonium hydrogen phosphate (DAP), were examined by density () and viscosity () measurements in order to investigate and analyze the solvation behavior that occurs in the ternary solutions (NA + KCl/DAP + water). All of these investigations were conducted at temperatures ranging from 293.
View Article and Find Full Text PDFAnal Chem
January 2025
State Key Laboratory of Surface Physics and Department of Physics, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Shanghai Key Laboratory of Metasurfaces for Light Manipulation, Fudan University, Shanghai 200433, China.
Numerous chemical reactions and most life processes occur in aqueous solutions, where the physical diffusion of small molecules plays a vital role, including solvent water molecules, solute biomolecules, and ions. Conventional methods of measuring diffusion coefficients are often limited by technical complexity, large sample consumption, or significant time cost. Here, we present an optical imaging method to study molecular diffusion by combining stimulated Raman scattering (SRS) microscopy with microfluidics: a "Y"-shaped microfluidic channel forming two laminar flows with a stable concentration gradient across the interface.
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