Eosinophilic Gastroentertis (EG) is a very rare disease, characterized by focal or difuse eosinophilic infiltration of the gastrointestinal tract. The clinical presentation is variable and depends on the histological and the extension layer involved. We report a case of eosinophilic gastroenteritis whose main presentation was ascites with peripheral eosinophilia and chronic intermittent diarrhea in a patient with a history of atopy. Upper endoscopy showed severe multifocal erythematous gastritis, the ascitic fluid showed elevated WBC with eosinophilia, with a SAAG (Serum albumin ascites gradient) of less 1.1. The patient was treated with corticoesteroids with remission of clinical manifestation.
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Arthritis Res Ther
January 2025
Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, the Ministry of Education Key Laboratory, Chinese Academy of Medical Sciences & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, China.
Objective: Severe gastrointestinal lesions are associated with a poor prognosis in eosinophilic granulomatosis with polyangiitis (EGPA). The goal of this study was to develop an effective predictive model for gastrointestinal lesions and to examine clinical patterns, associated factors, treatment, and outcomes of gastrointestinal lesions in EGPA.
Methods: We retrospectively enrolled 165 EGPA patients.
BMC Pediatr
December 2024
Department of Pediatrics, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing312000, China.
Background: Eosinophilic Gastrointestinal Disorders beyond Eosinophilic Esophagitis (non-EoE EGIDs) are chronic rare inflammatory disorders characterized by eosinophilic infiltration of the gastrointestinal (GI) tract.
Case Presentation: We report the first pediatric case of eosinophilic duodenitis (one type of the non-EoE EGIDs) with concomitant pancreatic reaction that was misdiagnosed as acute pancreatitis (AP). A 13-year-old girl was admitted to our hospital for a week of abdominal distension, vomiting, and epigastric pain that worsened recently.
Am J Transl Res
November 2024
Department of Pediatrics, Zhejiang Provincial Integrated Chinese and Western Medicine Hospital Hangzhou 310003, Zhejiang, China.
Eosinophilic gastroenteritis (EGE) is an inflammatory disease characterized by a significant increase in eosinophils. EGE itself is rare, and cases with clinical manifestations of hemorrhagic ascites are even rarer, which undoubtedly increases the risk of misdiagnosis. Given this, this study reports a rare case of pediatric EGE presenting with paroxysmal abdominal pain without apparent cause, accompanied by acute tonsillitis and mesenteric lymphadenitis, suggesting a possible intestinal infection.
View Article and Find Full Text PDFEosinophilic gastroenteritis is characterized by eosinophilic infiltration of the stomach and intestine. It is a rare disorder with bizarre presentations, making it difficult to diagnose and often leading to misdiagnoses. It can present with abdominal pain, diarrhea, vomiting, obstruction, ascites, etc.
View Article and Find Full Text PDFCureus
October 2024
Internal Medicine, Sheikh Shakhbout Medical City, Abu Dhabi, ARE.
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