Choroidal osteoma is an unusual form of intraocular calcification seen in otherwise healthy eyes. It is a benign idiopathic osseous tumor of the choroid, typically seen in young females. Choroidal neovascular membrane (CNVM) is a complication seen in one-third of these patients and carries a poor visual outcome. We report a case of a 25-year-old hyperthyroid female with choroidal osteoma and subfoveal CNVM in her left eye which was successfully treated using low-fluence photodynamic therapy (PDT) with verteporfin followed by a single injection of intravitreal ranibizumab.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159327PMC
http://dx.doi.org/10.4103/0301-4738.83622DOI Listing

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Article Synopsis
  • The study examined 80 Indian patients with choroidal osteoma, focusing on demographic and clinical characteristics as well as treatment outcomes.
  • Most patients were female (61%), with the majority in their second decade of life; various associated complications like choroidal neovascularization (CNV) were noted in 40% of eyes.
  • Treatment methods included anti-VEGF therapy for CNV and other procedures, with mean best corrected visual acuity improving slightly over a follow-up period, indicating the need for ongoing monitoring despite the generally benign nature of the condition.
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Choroidal osteoma is a rare, benign, osseous choristoma presenting as an orange-yellow, well-defined fundus mass. It presents unilaterally in most cases, has a predilection for the female sex, and favor a juxtapapillary location, becoming clinically manifest when it involves the macula. Almost 60% of eyes with osteoma may suffer significant visual loss.

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Purpose: To describe the use of anti-osteoclastic medications (i.e., bisphosphonates and receptor activator of nuclear factor kappa beta (RANK) ligand inhibitors) in treating choroidal osteoma.

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A choroidal osteoma (CO) is a relatively rare, benign tumor with ossification that develops in the choroid and undergoes enlargement and decalcification in its natural course. Photodynamic therapy (PDT) is used to induce decalcification, but there are few reports on individual cases treated with PDT. A 47-year-old Japanese man who had reduced decimal visual acuity (VA) of the right eye to 0.

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