AI Article Synopsis
- Two cases of renal transplant patients developed sebaceous hyperplasia due to cyclosporine treatment.
- Both patients were treated successfully with isotretinoin, showing good tolerance and no negative effects on kidney function.
- This study suggests that oral isotretinoin is a safe and effective option for treating sebaceous hyperplasia in kidney transplant recipients who are on cyclosporine.
Article Abstract
We present two cases of cyclosporine-induced sebaceous hyperplasia in renal transplant recipients, successfully treated with isotretinoin. Both patients tolerated isotretinoin well, with no alteration in graft function. These cases provide support for the safe and effective use of oral isotretinoin in the treatment of cyclosporine-induced sebaceous hyperplasia in the kidney transplant population.
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| http://dx.doi.org/10.1111/j.1440-0960.2011.00776.x | DOI Listing |
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A Case of Cyclosporine-Induced Sebaceous Hyperplasia in a Renal Transplant Patient Successfully Treated with Isotretinoin.
Ann Dermatol
April 2016
Department of Dermatology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Cyclosporine-induced sebaceous hyperplasia (SH) is a well-documented entity, occurring in up to 30% of renal transplant patients treated with cyclosporine and has also been reported to occur following heart or hematopoetic stem cell transplantation (HCST). Cyclosporine has a stimulatory effect on undifferentiated sebocytes, resulting in the clinical and histologic findings in these patients. Sebaceous hyperplasia most commonly presents as asymptomatic papules over the face, chest, or groin.
View Article and Find Full Text PDFSuccessful treatment of cyclosporine-induced sebaceous hyperplasia with oral isotretinoin in two renal transplant recipients.
Australas J Dermatol
August 2011
Department of Medicine (Dermatology), St Vincent's Hospital, Melbourne, Victoria, Australia.
Article Synopsis
- Two cases of renal transplant patients developed sebaceous hyperplasia due to cyclosporine treatment.
- Both patients were treated successfully with isotretinoin, showing good tolerance and no negative effects on kidney function.
- This study suggests that oral isotretinoin is a safe and effective option for treating sebaceous hyperplasia in kidney transplant recipients who are on cyclosporine.
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