New antioxidant bibenzyl derivative and isoflavonoid from the Tunisian Salsola tetrandra Folsk.

Nat Prod Res

Department of Chemistry, Laboratory of Natural Products, Faculty of Sciences, University of Monastir, Monastir 5000, Tunisia.

Published: April 2012

Two new phytochemical compounds, Tetranins A and B, 1-(3,5'-dihydroxy-4'-méthoxyphenyl)-2-phenylethanol 1 and 5,2'-dihydroxy-5'-methoxy-6,7-methylenedioxy-isoflavone 2, were isolated from the EtOAc extract of Salsola tetrandra roots. They exhibited a significant antioxidant effect in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and 2,2'-azinobis (3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assays. Their structures were elucidated by extensive spectroscopic methods including 1-D-((1)H and (13)C) and 2-D-NMR experiments (CHcorr, HMBC, (1)H-(1)H COSY and NOESY) as well as high-resolution ES-MS and they were found to be quite active as antioxidants in the DPPH and ABTS assays.

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http://dx.doi.org/10.1080/14786419.2010.536950DOI Listing

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