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Dermatofibrosarcoma Protuberans: The Impact of the Surgical Incision Site in Relation to Tumor Recurrence.
Cureus
December 2024
Pathology, Avalon University School of Medicine, Willemstad, CUW.
Dermatofibrosarcoma protuberans (DFSP) is a rare, locally invasive cutaneous sarcoma with a high propensity for recurrence, even following complete surgical excision. DFSP exhibits a low metastatic potential and is characterized by a distinctive honeycomb-like architecture composed of uniformly arranged spindle cells that frequently show CD34 immunostaining. Common surgical approaches include wide local excision (WLE), Mohs micrographic surgery (MMS), and, in severe cases, amputation.
View Article and Find Full Text PDFSurgical Excision of Pulmonary Metastases of Dermatofibrosarcoma Protuberans.
Cureus
October 2024
Thoracic Surgery, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Università Cattolica del Sacro Cuore, Roma, ITA.
Dermatofibrosarcoma protuberans (DFSP) is a rare malignancy of mesenchymal origin of medium-low grade with a tendency to local recurrences but not to distant metastases. We present the case of a 37-year-old male who underwent surgical resection of a 1.2 cm DFSP lesion on the left shoulder in May 2020.
View Article and Find Full Text PDFSurgical Management of Pediatric Dermatofibrosarcoma Protuberans: About Two Challenging Case Reports.
Glob Pediatr Health
September 2024
Pediatric Plastic surgery Unit, Children's Hospital of Rabat, Morocco.
Article Synopsis
- Dermatofibrosarcoma protuberans (DFSP) is a rare but locally aggressive skin tumor in children, known for slow growth and low likelihood of spreading, yet it often goes misdiagnosed due to its nonspecific symptoms.
- Diagnosing DFSP can be difficult because it may present as nodular lesions or resemble other conditions like vascular malformations, highlighting the need for histologic and immunohistochemical examinations.
- Successful treatment involves complete surgical removal with wide margins, as seen in two pediatric cases where lesions initially mimicked vascular issues, resulting in no recurrences after follow-ups of 6 months and 2 years, with ongoing monitoring planned for at least 5 years.
Dermatofibrosarcoma protuberans of the breast: A rare breast tumor mimicking a cutaneous lesion.
Int J Surg Case Rep
October 2024
Department of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy; Breast Unit, University Hospital Federico II, Naples, Italy.
Article Synopsis
- Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue tumor typically occurring in adults aged 20-50, presenting as a slow-growing skin nodule that can become prominent if not treated.
- Two case studies are presented: a 22-year-old woman with a nodule in her left breast initially misdiagnosed, and a 54-year-old woman with a growing lump in her right breast, both confirmed to be DFSP after excision.
- DFSP is a low-grade sarcoma that needs early diagnosis and surgical removal to prevent complications; while surgery is the main treatment, other options like Mohs surgery or Imatinib exist for difficult cases.
Combined use of composite mesh and acellular dermal matrix graft for abdominal wall repair following tumour resection.
World J Surg Oncol
August 2024
Department of Surgery, Virgen de la Arrixaca University Hospital, Ctra. Madrid-Cartagena s/n, Murcia, 30120, Spain.
Article Synopsis
- - Surgeries for abdominal wall sarcomas often involve extensive resections that create complex defects, but using both porcine dermal xenografts and composite meshes can help with repair while reducing complications.
- - A study involving 19 patients (average age 53.2 years) identified various types of sarcomas and demonstrated that surgical resections and reconstructions using these materials can be effective.
- - After an average follow-up of 38 months, complications occurred in about 31.5% of patients, including wound issues and one death, but overall, the technique showed promising medium-term results.
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