AI Article Synopsis
- A 28-year-old non-smoker experienced a significant pulmonary embolism and left pleural effusion, likely linked to four months of treatment with olanzapine (10 mg daily).
- After discontinuing the antipsychotic and undergoing thrombolytic therapy, the patient fully recovered in 18 days.
- The relationship between antipsychotic medications and thrombotic events is still debated, including their occurrence rates, risk factors, and underlying biological mechanisms in psychiatric patients.
Article Abstract
We report the case of a 28 years old, non-smoker male with a massive pulmonary embolism and left pleural effusion associated and probably induced by olanzapine 10 mg once daily in the previous 4 months, completely recovered after 18 days of stopping the antipsychotic and trombolytic treatment. Thrombotic events have been reported with the use of antipsychotic compounds, although the incidence, predisposing factors, and biological mechanisms associated with these events in psychiatric patients are subject to debate.
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