NEAR-INFRARED DYES: Probe Development and Applications in Optical Molecular Imaging.

Curr Org Synth

Vanderbilt University Institute of Imaging Science, Vanderbilt University, 1161 21 Avenue South, Medical Center North, AA-1105, Nashville, TN 37232-2310.

Published: August 2011

The recent emergence of optical imaging has brought forth a unique challenge for chemists: development of new biocompatible dyes that fluoresce in the near-infrared (NIR) region for optimal use in biomedical applications. This review describes the synthesis of NIR dyes and the design of probes capable of noninvasively imaging molecular events in small animal models.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150548PMC
http://dx.doi.org/10.2174/157017911796117223DOI Listing

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