A 44 year old white woman with rheumatoid arthritis for 19 years developed subcorneal pustular dermatosis. She had increased polyclonal IgA and IgA rheumatoid factor. After 4 months' treatment with dapsone 100 mg daily the patient had neither skin lesions nor active joint disease.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1004020PMC
http://dx.doi.org/10.1136/ard.49.3.190DOI Listing

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