The lipid formulation of amphotericin B is the initial drug of choice for central nervous system blastomycosis, but it is costly and associated with significant toxicity. This case report details a patient with primary pulmonary blastomycosis with dissemination to the skin, one joint, and the brainstem that was successfully treated solely with high-dose fluconazole.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355743 | PMC |
http://dx.doi.org/10.3121/cmr.2011.1023 | DOI Listing |
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