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Early Achievement of High Treatment Targets in Moderate-to-Severe Atopic Dermatitis with Upadacitinib: Real-World Evidence from the Observational UP-TAINED Study.
Dermatol Ther (Heidelb)
March 2025
Department of Dermatology, Ludwig-Maximilians University Hospital, Munich, Germany.
Introduction: Phase 3 clinical trials have demonstrated robust efficacy and favorable safety of upadacitinib for the treatment of atopic dermatitis (AD). However, real-world data are still sparse. The objectives of this study were to assess the effectiveness and safety of real-world treatment with upadacitinib in patients with moderate-to-severe AD.
View Article and Find Full Text PDFClinical Presentation and Histopathological Characteristics of Sporotrichosis.
J Cosmet Dermatol
March 2025
Department of Dermatology, The 2nd Hospital of Harbin Medical University, Harbin, China.
Objective: Sporotrichosis is the most prevalent deep mycosis worldwide. The differential diagnosis of its clinical symptoms and histopathological features presents considerable complexity. A thorough understanding of the clinical manifestations and pathological characteristics of sporotrichosis is crucial for its accurate clinical diagnosis.
View Article and Find Full Text PDFRecommendations on how to proceed in case of suspected allergy to penicillin/β-lactam antibiotics: Position paper of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Society for Pediatric Allergology (GPA), Austrian Society for Allergology and Immunology (ÖGAI) and the Swiss Society for Allergology and Immunology (SGAI).
Allergol Select
March 2025
Allergology and Immunology, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
β-lactam antibiotics (BLAs) are still the antibiotics of first choice for the treatment of many bacterial infections. Treatment with a BLA is often hindered by a suspected allergy, up to 10% of the population report an allergy to penicillin. After allergological evaluation of the suspected allergic reaction to a BLA, most patients show a low probability of a BLA allergy; only in a minority of cases an allergic reaction to the repeated administration of a BLA appear likely in view of the previous history.
View Article and Find Full Text PDFCase Report: Anti-interferon-γ autoantibodies in an adolescent with disseminated and mycobacterial co-infections.
Front Pediatr
February 2025
Department of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Background: Anti-interferon-γ autoantibodies (AIGAs) are associated with adult-onset immunodeficiency syndrome, which makes individuals susceptible to intracellular pathogen infections. However, AIGAs are rarely reported in adolescents.
Case Presentation: We report a 13-year-old Chinese boy who presented with fever, cough, and enlarged cervical lymph nodes.
Cross-sectional study on the seroprevalence, reinfection, and associated factors of Chlamydia trachomatis among female sex workers in Guangdong Province, China.
BMC Infect Dis
March 2025
Dermatology Hospital, Southern Medical University, 2 Rujing Rd, Yuexiu District, Guangzhou City, China.
Background: Female sex workers (FSWs) are at high risk of chlamydia infection, yet the seroprevalence among FSWs in China remains unclear. This study aimed to determine the seroprevalence of Chlamydia trachomatis and associated factors among FSWs in Guangdong Province, China.
Methods: A cross-sectional study was conducted among FSWs in two cities in Guangdong Province.
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