Objective: The objective of this study was to evaluate hearing loss among workers exposed to styrene, alone or with noise.
Design: This cross-sectional study was conducted as part of NoiseChem, a European Commission 5th Framework Programme research project, by occupational health institutes in Finland, Sweden, and Poland.
Study Sample: Participants' ages ranged from 18-72 years (n = 1620 workers). Participants exposed to styrene, alone or with noise, were from reinforced fiberglass products manufacturing plants (n = 862). Comparison groups were comprised of workers noise-exposed (n = 400) or controls (n = 358). Current styrene exposures ranged from 0 to 309 mg/m(3), while mean current noise levels ranged from 70-84 dB(A). Hearing thresholds of styrene-exposed participants were compared with Annexes A and B from ANSI S3.44, 1996.
Results: The audiometric thresholds of styrene exposed workers were significantly poorer than those in published standards. Age, gender, and styrene exposure met the significance level criterion in the multiple logistic regression for the binary outcome 'hearing loss' (P = 0.0000). Exposure to noise (<85 dBA p = 0.0001; ≥85 dB(A) p = 0.0192) interacted significantly with styrene exposure.
Conclusions: Occupational exposure to styrene is a risk factor for hearing loss, and styrene-exposed workers should be included in hearing loss prevention programs.
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http://dx.doi.org/10.3109/14992027.2011.588965 | DOI Listing |
J Hazard Mater
December 2024
College of Environmental Science and Engineering, North China Electric Power University, Beijing 102206, China. Electronic address:
This study aimed to investigate the differences in the mechanisms of microscopic hepatotoxicity, developmental toxicity, and neurotoxicity in aquatic organisms co-exposed to styrene-butadiene rubber tire microplastics (SBR TMPs) and fluoroquinolone antibiotics (FQs). We found that hepatotoxicity in zebrafish induced by SBR TMPs and FQs was significantly higher than developmental toxicity and neurotoxicity. Furthermore, the main effects of the FQs primarily manifested as synergistic toxicity, whereas the low- and high-order interactions of the FQs mainly exhibited synergistic and antagonistic effects, respectively.
View Article and Find Full Text PDFObjectives: According to the International Agency for Research on Cancer, styrene is probably carcinogenic for lymphohaematopoietic neoplasms, with insufficient evidence for other cancer sites. We compared mortality and cancer incidence (for the first time) in a UK cohort occupationally exposed to high levels of styrene to that of the general population of England and Wales.
Methods: The follow-up for mortality ran from 1969 to 2022, while the follow-up for cancer incidence ran from 1971 to 2020.
Int J Mol Sci
November 2024
Department of Biophysics of Environmental Pollution, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska Str. 141/143, 90-236 Lodz, Poland.
The aim of the present study was to investigate the concentration- and size-dependent effects of non-functionalized polystyrene nanoparticles (PS-NPs) of varying diameters (29 nm, 44 nm, and 72 nm) on specific epigenetic modifications and gene expression profiles related to carcinogenesis in human peripheral blood mononuclear cells (PBMCs) in vitro. This in vitro human-cell-based model is used to investigate the epigenetic effect of various environmental xenobiotics. PBMCs were exposed to PS-NPs at concentrations ranging from 0.
View Article and Find Full Text PDFSci Rep
December 2024
Egyptian Petroleum Research Institute, Nasr City, 11727, Cairo, Egypt.
This study aims to develop a series of cation exchange hydrogel resins via gamma irradiation technique through copolymerizing styrene sodium sulfonate with three acrylamide derivatives (designated as poly(X-co-styrene sodium sulfonate), where X refers to acrylamide (PAASS), methacrylamide (PMASS), and isopropyl acrylamide (PIASS)). The prepared hydrogel resins were characterized and tested for the adsorption removal of hard/scale metal cations (e.g.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Cell Biology Laboratory, Institute of Biological and Health Sciences, Federal University of Alagoas, Maceio, Brazil.
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