AI Article Synopsis
- The study examined the link between white blood cell (WBC) count at admission and short-term outcomes (death or dependency) in patients with acute cerebral infarction.
- A total of 2808 patients were analyzed, with WBC counts recorded within 24 hours of admission and their clinical outcomes assessed by neurologists.
- Higher WBC counts were found to correlate with increased odds of death and dependency, indicating that a rise in WBC count is a negative predictor for patient outcomes in acute cerebral infarction.
Article Abstract
Purpose: We studied the association between admission white blood cell (WBC) count and short term outcome in patients with acute cerebral infarction.
Methods: 2808 patients with acute cerebral infarction were included in the study. WBC count and other variables were collected within the first 24 hours of admission. Clinical outcomes (death or dependency) were evaluated by neurologists during hospitalization. The associations between WBC count and in-hospital death or dependency at discharge were analyzed using a multiple logistic model.
Result: Multivariate-adjusted odds ratio (95% confidence intervals) of dependency associated with patients with WBC of 10.0-10.9×109/L, 11.0-11.9×109/L, ≥12.0×109/L were 1.46(0. 87-2. 45), 6.21(3. 70-10. 42) and 7.01(4. 53-10. 87), respectively, when compared with patients with admission WBC counts < 10.0x109/L. Multivariate-adjusted odds ratio (95% confidence intervals) of death associated with WBC 10.0-10.9×109/L, 11.0-11.9×109/L and ≥12.0×109/L were 2.098(0. 96-4. 58), 4.79(2. 24-10. 22) and 5.59(3. 14-9. 98), respectively.
Conclusion: Increased WBC count at admission was significantly and positively associated with in-hospital death or dependency at discharge among patients with acute cerebral infarction.
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| http://dx.doi.org/10.25011/cim.v34i4.15368 | DOI Listing |
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