We report on high efficiency resonant doubling to 486 nm using periodically poled KTP. The IR laser source is an FBG stabilized semiconductor laser with a maximum polarization maintaining (PM) fiber coupled output of 840 mW. An output power of 680 mW at 486 nm was obtained from our optimized cavity, giving net efficiency of 81%. Also, we report an 87.5% net efficiency in coupling of this blue light from the servo locked cavity into a single-mode PM fiber. This gives a total of 71% fiber to fiber efficiency. Furthermore, a wall plug efficiency of 21.4% was obtained.
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http://dx.doi.org/10.1364/OL.36.002940 | DOI Listing |
Cureus
December 2024
Anaesthesiology and Critical Care, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.
Background: Ultrasonographic measurement of optic nerve sheath diameter (ONSD) has been proposed as a non-invasive, bedside method to detect raised intracranial pressure (ICP) in various clinical settings. We aimed to correlate the ONSD obtained by ultrasonography (USG) with the ONSD obtained by magnetic resonance imaging (MRI) and to find its measurement accuracy.
Methodology: A prospective double-blind study was carried out by performing ocular ultrasounds on 32 patients with clinical features of intracranial hypertension.
Neurology
February 2025
Department of Neurology and Center of Clinical Neuroscience, First Medical Faculty, General University Hospital and Charles University, Prague, Czech Republic.
Background And Objectives: Patients with multiple sclerosis (MS) may demonstrate better disease control when treatment is initiated on high-efficacy disease-modifying therapies (DMTs) from onset. This subgroup analysis assessed the long-term efficacy and safety profile of the high-efficacy DMT ocrelizumab (OCR) as first-line therapy for early-stage relapsing MS (RMS).
Methods: Post hoc exploratory analyses of efficacy and safety were performed in a subgroup of treatment-naive patients with RMS who received ≥1 dose of OCR in the multicenter OPERA I/II (NCT01247324/NCT01412333) studies.
Chem Sci
January 2025
Shenzhen Key Laboratory of New Information Display and Storage Materials, College of Materials Science and Engineering, Shenzhen University Shenzhen 518060 P. R. China
Developing highly efficient deep-blue multi-resonance thermal activated delayed fluorescence (MR-TADF) materials for ultra-high-definition organic light-emitting diodes (OLEDs) displays that meet the stringent BT.2020 standard remains a significant challenge. In this study, we present a strategy to achieve high-performance deep-blue MR-TADF emitters by integrating a large π-conjugated double-boron-embedded MR skeleton with strategically positioned peripheral steric hindrance groups.
View Article and Find Full Text PDFJCEM Case Rep
February 2025
First Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.
SARS-CoV-2 infection could trigger autoimmune disease. We report a case of concomitant exacerbation of Graves orbitopathy (GO) and myasthenia gravis (MG) after SARS-CoV-2 infection. A 43-year-old woman had diplopia, proptosis, and swollen eyelids.
View Article and Find Full Text PDFJ Exp Clin Cancer Res
January 2025
Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
Background: Colorectal cancer (CRC) has high incidence and mortality rates, with severe prognoses during invasion and metastasis stages. Despite advancements in diagnostic and therapeutic technologies, the impact of the tumour microenvironment, particularly extracellular matrix (ECM) stiffness, on CRC progression and metastasis is not fully understood.
Methods: This study included 107 CRC patients.
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