AI Article Synopsis
- This text discusses a unique case of reversible cerebral vasoconstriction syndrome (RCVS) occurring in a patient with Takayasu's arteritis (TA), which presented with intense headaches and seizures.
- Imaging studies showed signs of posterior reversible encephalopathy syndrome and significant vasoconstriction in various arteries.
- The authors suggest that RCVS should be considered when diagnosing thunderclap headaches with related vascular abnormalities in patients with connective tissue diseases like Takayasu's arteritis.
Article Abstract
We herein present the first reported case of reversible cerebral vasoconstriction syndrome (RCVS) in Takayasu's arteritis (TA), in a patient with severe thunderclap headache and generalized tonic-clonic seizure. Magnetic resonance imaging and angiography revealed posterior reversible encephalopathy syndrome, followed by severe vasoconstriction in multiple arteries. RCVS should be included in the differential diagnosis of thunderclap headache attacks with radiologic intracranial vascular abnormalities in connective tissue diseases, including TA.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2169/internalmedicine.50.5185 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Inhibition of RIPK1-driven necroptosis ameliorates inflammatory hyperalgesia caused by lipopolysaccharide: involvement of TLR-, NLRP3-, and caspase-11-mediated signaling pathways.
Cell Mol Biol (Noisy-le-grand)
January 2025
Department of Pharmacology, Faculty of Pharmacy, Mersin University, Mersin, Türkiye.
Increasing evidence suggests that inhibition of receptor-interacting serine/threonine-protein kinase (RIPK) 1/RIPK3/mixed lineage kinase domain-like pseudokinase (MLKL) necrosome has protective effects in vivo models of painful conditions seen in humans associated with inflammation and demyelination in the central nervous system. However, the contribution of RIPK1-driven necroptosis to inflammatory pain remains unknown. Therefore, this study aims to determine the effect of necrostatin (Nec) -1s, a selective RIPK1 inhibitor, on lipopolysaccharide (LPS)-induced inflammatory pain and related underlying mechanisms.
View Article and Find Full Text PDFPredictors of Outcome in Patients with Presumed Reversible Cerebral Vasoconstriction Syndrome (RCVS).
J Stroke Cerebrovasc Dis
January 2025
Department of Neurosurgery, University of Illinois Chicago, Chicago, IL. Electronic address:
Introduction: Reversible cerebral vasoconstriction syndrome (RCVS) is thought to be benign by nature, but a proportion of patients still suffer from neurological deficits on follow-up.
Objective: To understand what factors may influence a patient's recovery from RCVS.
Methods: The Clinical Research Data Warehouse at this institution was employed to search the medical records for patients with diagnosis and treatment of RCVS (2010-2021).
The effects of corticotropin-releasing factor (CRF) and urocortins on the serotonin (hydroxytryptamine, 5HT) released from the raphe nuclei (RN).
Neuropeptides
January 2025
Department of Pathophysiology, Faculty of Medicine, University of Szeged, Hungary.
Corticotropin-releasing factor (CRF) and urocortins (UCN1, UCN2 and UCN3) belong to the same CRF family of neuropeptides. They regulate the neuroendocrine, autonomic and behavioral responses to stress via two CRF receptors (CRF1 and CRF2). Stress, anxiety and depression affects the activity of the hypothalamic-pituitary-adrenal (HPA) axis and the serotoninergic neurotransmission, both being regulated by CRF and CRF-related peptides.
View Article and Find Full Text PDFFocal volume reduction in transcranial focused ultrasound using spherical wave expansions.
Ultrasonics
January 2025
School of Biological Science and Medical Engineering, Beihang University, Beijing, China. Electronic address:
Transcranial focused ultrasound (tFUS) has been gaining increased attention as a non-invasive modality for treating brain diseases. However, accurately focusing on brain structures remains a challenge as the ultrasound is severely distorted by the presence of the skull. In this article, we propose a promising distortion correction method based on spherical wave expansions.
View Article and Find Full Text PDFTrehalose Inhibits ferroptosis Through Activating SIRT3/SOD2 Signaling Axis and Alleviates Brain Injury After Traumatic Brain Injury.
Neurochem Res
January 2025
Wuxi School of Medicine, Jiangnan University, Wuxi, 214122, China.
Trehalose has neuroprotective effects in neurodegenerative diseases. This study aimed to explore the impact of trehalose on traumatic brain injury (TBI) by investigating its role in neuroprotection. The TBI mice model was established utilizing the cortical impact technique followed by trehalose treatment.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!