Yojironins E-I, prenylated acylphloroglucinols from Hypericum yojiroanum.

Bioorg Med Chem Lett

Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.

Published: September 2011

Five new prenylated acylphloroglucinols, yojironins E-Ι (1-5), were isolated from the whole plants of Hypericum yojiroanum. Their structures were elucidated by spectroscopic data. Yojironin E (1) exhibited antimicrobial activity against Aspergillus niger, Candida albicans, Cryptococcus neoformans, and Trichophyton mentagrophytes.

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http://dx.doi.org/10.1016/j.bmcl.2011.07.004DOI Listing

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