The potential relation of biomechanical indices with topographic features in keratoconus was studied using multifactor correlation analysis. Topographic features in keratoconus were found to have influence on biomechanical measurements in the central zone of the cornea. If the zone of ectasia is distant from the central part of the cornea the central biomechanics can remain normal. Elasticity coefficient was found to be the most sensitive and keratoconus topography-dependent biomechanical index compared with other biomechanical parameters studied in this work.
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