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SINE retrotransposons import polyadenylation signals to 3'UTRs in dog (Canis familiaris).
Mob DNA
January 2025
Department of Biology, La Sierra University, Riverside, CA, USA.
Background: Messenger RNA 3' untranslated regions (3'UTRs) control many aspects of gene expression and determine where the transcript will terminate. The polyadenylation signal (PAS) AAUAAA (AATAAA in DNA) is a key regulator of transcript termination and this hexamer, or a similar sequence, is very frequently found within 30 bp of 3'UTR ends. Short interspersed element (SINE) retrotransposons are found throughout genomes in high copy numbers.
View Article and Find Full Text PDFEffects of culturally-appropriate group education for migrants with type 2 diabetes in primary healthcare: pre-test-post-test design.
BMC Prim Care
January 2025
Department of Public Health and Caring Sciences, Uppsala University, P O Box 564, Uppsala, S-751 22, Sweden.
Background: The global incidence of type 2 diabetes is rapidly rising, particularly among migrants in developed countries. Migrants bear a significant burden of diabetes. However, this study is the only to evaluate the effects of a culturally appropriate diabetes intervention for these migrants on diabetes knowledge and health outcomes, adding a novel perspective to the existing literature.
View Article and Find Full Text PDFThree-year-old development: The relationship of child health and parenting stress to neurocognition.
J Pediatr Nurs
January 2025
Department of Health Promotion and Disease Prevention, College of Nursing, University of Tennessee Health Science Center, 847 Union Ave, Memphis, TN 38163, USA.
Purpose: This study examined parenting stress and child special healthcare needs to child neurocognitive development (NCD).
Design And Methods: This secondary analysis used data from the primary study, a longitudinal cohort study of mother-child dyads. Multivariable regression models examined the associations between parenting stress and child special healthcare needs with NCD.
Prediction of real-time cine-MR images during MRI-guided radiotherapy of liver cancer using a GAN-ConvLSTM network.
Med Phys
January 2025
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Respiratory motion during radiotherapy (RT) may reduce the therapeutic effect and increase the dose received by organs at risk. This can be addressed by real-time tracking, where respiration motion prediction is currently required to compensate for system latency in RT systems. Notably, for the prediction of future images in image-guided adaptive RT systems, the use of deep learning has been considered.
View Article and Find Full Text PDFMulti-generational exposure of Daphnia magna to pharmaceuticals: Effects on colonization, reproduction, and habitat selection behavior.
Ecotoxicol Environ Saf
January 2025
Department of Ecology and Coastal Management, Institute of Marine Sciences of Andalusia (ICMAN - CSIC), Puerto Real 11519, Spain. Electronic address:
The presence of pharmaceuticals in the aquatic environment is increasing due to their growing use for human health. Although most studies are based on short exposures to these contaminants, the present study has emerged from the need to study pharmaceuticals in aquatic organisms over a long-term exposure to understand any multi-generational chronic effects and alterations regarding habitat selection. Therefore, this study shows: (1) the ability of Daphnia magna to colonize environments contaminated with caffeine, ibuprofen and fluoxetine, and (2) the effect of these pharmaceuticals on reproduction and habitat selection (under two scenarios: with and without food) after a long-term exposure period of three generations.
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