Objectives: To evaluate intraobserver and interobserver agreement of manually encompassed lung lesions for perfusion measurements using volume-perfusion computed tomography (VPCT).
Materials And Methods: Institutional review board approval and informed consent were obtained. HIPAA guidelines were followed. A 65-s dynamic study was acquired with scan parameters 80 kV, 60 mAs (80 mAs for patients ≥ 70 kg), 128 × 0.6mm collimation. Blood flow (BF), blood volume (BV) and K(trans) parameters were determined by syngo volume perfusion CT body with 88 lesions analyzed retrospectively.
Results: Within-subject coefficients of variation for intraobserver agreement (range 6.59-12.82%) were superior to those for interobserver agreement (range 21.75-38.30%). Size-dependent analysis revealed lower agreements for lesions <4 cm as compared to larger lesions. Additionally, agreements of the upper, middle and lower lung zones were different.
Conclusions: Intraobserver agreement was substantial for VPCT lung cancer perfusion measurements encouraging the use for tumor characterization and therapy response monitoring. Interobserver agreement is limited and unexperienced readers should be trained before using this new method.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ejrad.2011.06.047 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Magnetic resonance imaging based anatomy of the conus medullaris: variations of location and morphology.
World Neurosurg
January 2025
Spine unit, Department of Orthopedics and Traumatology, Elhadara University Hospital, Alexandria University, Egypt.
Background: In adults, the conus medullaris( CM) tip usually terminates at the mid aspect of the L1 vertebra. However, variations exist. Beside the location, differences in the CM's shape are believed to be closely related to neurological conditions.
View Article and Find Full Text PDFUsefulness of Dual-Energy CT for Differentiating Hemorrhage From Iodine Extravasation in Meningiomas After Preoperative Embolization.
J Comput Assist Tomogr
November 2024
From the Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, Kumamoto.
Objective: Discriminating between hemorrhage and iodine extravasation can pose challenges in conventional computed tomography (CCT) images following preoperative embolization for meningioma. This study aimed to assess the efficacy of dual-energy computed tomography (DECT) in differentiating hemorrhage from iodine extravasation after preoperative embolization for meningioma.
Methods: Twenty-one consecutive meningioma patients who underwent CCT before and DECT immediately after preoperative embolization were included in this study.
Not all stains are made equal: impact of stain normalization on prostate cancer diagnosis.
Pathologica
October 2024
Biolab, PoliToBIOMed Lab, Department of Electronics and Telecommunications, Politecnico di Torino, Turin, Italy.
Objective: Stain normalization is a technique used to standardize the color appearance of digital whole slide images (WSIs). This study aimed to assess the impact of digital stain normalization on prostate cancer diagnosis by pathologists.
Methods: A multi-institutional board of four pathologists evaluated 407 hematoxylin and eosin (H&E) prostate WSIs before and after stain normalization.
Background: Lip and oral cavity cancer is leading cause of cancer mortality among Indian men. This study evaluated diagnostic accuracy of mobile health (mHealth) enabled screening for early detection of oral premalignant lesions or oral cancer (OPML/OC). It also described epidemiology of tobacco and other substance use and associated oral lesions in rural northern India.
View Article and Find Full Text PDFIntra- and interobserver agreement in evaluation of image-defined risk factors on computed tomography in pediatric neuroblastoma.
Pediatr Radiol
January 2025
Izaak Walton Killam Health Centre, Halifax, Nova Scotia, B3K 6R8, Canada.
Background: Image-defined risk factors (IDRFs) were introduced to provide a consensus approach for pre-treatment risk stratification on computed tomography (CT) and magnetic resonance imaging (MRI) in patients with neuroblastoma.
Objective: To assess the intra- and inter-reader agreement of radiologists in identifying IDRFs on CT.
Materials And Methods: Approval for this retrospective study was granted by our institutional research ethics board with a waiver of consent.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!