Although there are some differential aspects related to peak bone mass acquisition and later bone loss throughout life between genders, the frequency of osteoporosis in young individuals is similar for both genders. In addition, in this population group, the development of osteoporosis is frequently associated with secondary causes. Indeed, nearly 50% of young individuals with osteoporosis have diseases or therapies related to the development of this disorder, with glucocorticoid therapy being one of the most frequently associated conditions. There are several other processes, which have also been associated with such a disorder in these individuals, but the causes differ between genders. In addition, idiopathic osteoporosis is also a frequent condition in these patients. In this subgroup of patients, a family history of osteoporosis or hypercalciuria is also a frequently associated finding. Because of that, in order to rule out secondary causes of osteoporosis, the laboratory studies performed to these patients should be extensive. Although there is few data on the treatment of these patients, basic rules such as exercise, correct calcium and vitamin D consumption, and avoiding alcohol and tobacco consumption should be advised. Drug therapy will depend on the cause of osteoporosis. However, it should be taken into account that most young women are of childbearing age, so drug therapy in these patients should be evaluated cautiously.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.reuma.2009.01.014 | DOI Listing |
An Pediatr (Engl Ed)
March 2025
Servicio de Pediatría, Enfermedades Infecciosas y Tropicales, Hospital Universitario La Paz, Fundación IdiPaz, CIBERINFEC, Madrid, Spain; Sociedad Española de Infectología Pediátrica (SEIP), Madrid, Spain.
Floods constitute one of the most widely described natural phenomena worldwide, and their frequency is increasing due to the consequences of climate change. Floods pose risks to the affected populations, including an increase in communicable diseases mainly due to population displacement and overcrowding, deficiencies in hygiene and dietary measures and difficulties accessing health care. The most frequently reported infectious diseases in the context of these disasters are gastrointestinal and respiratory diseases and diseases resulting from wound infection.
View Article and Find Full Text PDFJ Arthroplasty
February 2025
Department of Orthopaedic Surgery, Northwell Orthopaedic Institute, Lenox Hill Hospital, New York, New York.
Background: Optimal coronal and rotational alignment in total knee arthroplasty is essential for satisfactory outcomes. There has been limited focus on sagittal alignment in assessing outcomes. This study investigated the impact of femoral implant flexion (FF) angle on knee kinematics and postoperative outcomes.
View Article and Find Full Text PDFInt Psychogeriatr
March 2025
Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China; International Research Center for Medicinal Administration, Peking University, Beijing 100191, China.
To examine the prevalence of treatment indications for antidepressants and assessed temporal trends in antidepressant prescribing for depression among adult patients in primary health care facilities (PHFs) in China. Descriptive study of antidepressant prescriptions written by primary care physicians. Setting participants: Patients aged 18 years and above in 67 PHFs in Dongcheng district in Beijing between 1 January 2014 and 31 December 2022.
View Article and Find Full Text PDFDent Mater
March 2025
Department of Conservative Dentistry and Periodontology, LMU University Hospital, LMU Munich, Goethestrasse 70, Munich 80336, Germany.
Objectives: The aim of this study was to examine the marginal seal of novel bioactive restorative materials and the material-related properties associated with bacterial microleakage.
Methods: Class II cavities prepared into human extracted teeth were restored with: Venus Diamond (VD) + selective enamel etching (SEE)/self-etching universal adhesive (SEA), ACTIVA BioACTIVE RESTORATIVE (AB) + SEE/SEA, Cention Forte (CF) + Cention Primer, Ketac Universal Aplicap (KU), EQUIA Forte HT (EF) and Surefil One (SO) and exposed to a cariogenic multi-species bacterial suspension for 7 days. Bacterial microleakage was visualized with a modified gram staining protocol and bacterial penetration depths were microscopically determined after sectioning the teeth.
ESC Heart Fail
March 2025
Institute of Health Informatics Research, University College London, London, UK.
Aims: Atrial fibrillation (AF) is a frequent comorbidity in heart failure (HF). We analysed factors associated with new-onset atrial fibrillation in patients with heart failure using linked real-world UK data from primary and secondary care, along with findings from genome-wide association studies.
Methods And Results: Among 163 174 participants with a diagnosis of HF (January 1998 to May 2016) from Clinical Practice Research Datalink (CPRD) and Hospital Episodes Statistics (HES), 111 595 participants had no previous history of AF (mean age 76.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!