We herein report a case of a 67-year-old diabetic woman who presented with a history of fatigue for 1 month. Her investigations showed proteinuria, active urine sediment, p-ANCA positivity and worsened renal functions. A diagnosis of rapidly progressive glomerulonephritis was made. Renal biopsy revealed class V (membranous) lupus nephritis with superimposed ANCA-associated crescentic glomerulonephritis. She was treated with steroids and cyclophosphamide. Two months later, she presented with cytomegalovirus colitis and deep vein thrombosis of right leg. The case reflects an interesting renal pathology, and complications of the disease per se and its treatment.
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