The efficient synthesis of various diborylalkenes such as 1,1-, trans-1,2-, and cyclic 1,2-diborylalkenes from alkenes and diboron was achieved for the first time. Selective preparation of di- and monoborylalkenes was also realized by the appropriate choice of reaction conditions. The reaction was found to proceed via a new mechanism of dehydrogenative borylation through a monoborylpalladium complex bearing an anionic PSiP-pincer ligand as a key intermediate, which realized the efficient borylation without sacrificial hydroboration or hydrogenation of the alkene.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ja205186k | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Generative design of crystal structures by point cloud representations and diffusion model.
iScience
January 2025
School of Physics and Electronic Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Efficiently generating energetically stable crystal structures has long been a challenge in material design, primarily due to the immense arrangement of atoms in a crystal lattice. To facilitate the discovery of stable materials, we present a framework for the generation of synthesizable materials leveraging a point cloud representation to encode intricate structural information. At the heart of this framework lies the introduction of a diffusion model as its foundational pillar.
View Article and Find Full Text PDFInterplay between energy metabolism and NADPH oxidase-mediated pathophysiology in cardiovascular diseases.
Front Pharmacol
January 2025
Department of Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Sustained production of reactive oxygen species (ROS) and an imbalance in the antioxidant system have been implicated in the development of cardiovascular diseases (CVD), especially when combined with diabetes, hypercholesterolemia, and other metabolic disorders. Among them, NADPH oxidases (NOX), including NOX1-5, are major sources of ROS that mediate redox signaling in both physiological and pathological processes, including fibrosis, hypertrophy, and remodeling. Recent studies have demonstrated that mitochondria produce more proteins and energy in response to adverse stress, corresponding with an increase in superoxide radical anions.
View Article and Find Full Text PDFExtracting Thin Film Structures of Energy Materials Using Transformers.
ACS Phys Chem Au
January 2025
Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States.
Neutron-Transformer Reflectometry Advanced Computation Engine (), a neural network model using a transformer architecture, is introduced for neutron reflectometry data analysis. It offers fast, accurate initial parameter estimations and efficient refinements, improving efficiency and precision for real-time data analysis of lithium-mediated nitrogen reduction for electrochemical ammonia synthesis, with relevance to other chemical transformations and batteries. Despite limitations in generalizing across systems, it shows promises for the use of transformers as the basis for models that could accelerate traditional approaches to modeling reflectometry data.
View Article and Find Full Text PDFScale-Up of Nanocorundum Synthesis by Mechanochemical Dehydration of Boehmite.
Ind Eng Chem Res
January 2025
Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim an der Ruhr, Germany.
This work presents the scale-up of room-temperature mechanochemical synthesis of nanocorundum (high-surface-area α-AlO) from boehmite (γ-AlOOH). This transformation on the 1 g scale using a laboratory shaker mill had previously been reported. High-energy Simoloyer ball mills equipped with milling chambers of sizes ranging from 1 to 20 L were used to scale up the mechanochemical nanocorundum synthesis to the 50 g to 1 kg scale, which paves the way to further increase batch size.
View Article and Find Full Text PDFRecent advances in microwave-assisted synthesis of triazoles and their derivatives: a green approach toward sustainable development methods.
RSC Adv
January 2025
Department of Chemistry, Manipal University Jaipur VPO-Dehmi-Kalan, Off Jaipur Ajmer Express Way Jaipur Rajasthan 303007 India
Triazole, a nitrogen-containing five-membered heterocycle with two isomeric forms, 1,2,3-triazole and 1,2,4-triazole, has proven to be a valuable component in the pharmaceutical domain. Owing to its widespread utility in drug development, pharmaceutical and medicinal chemistry, several synthetic methods have been explored, such as different catalytic systems, solvents, and heating methodologies in recent years. However, some methods were associated with several limitations, such as harsh reaction conditions, high temperatures, low atom economy, and long reaction times.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!