The capabilities of cross-polarization optical coherence tomography (CP OCT) for early bladder-cancer detection are assessed in statistical study and compared with the traditional OCT. Unlike the traditional OCT that demonstrates images only in copolarization, CP OCT acquires images in cross-polarization and copolarization simultaneously. 116 patients with localized flat suspicious lesions in the bladder were enrolled, 360 CP OCT images were obtained and analyzed. CP OCT demonstrated sensitivity 93.7% (vs. 81.2%, <0.0001), specificity 84% (vs. 70.0%, <0.001) and accuracy 85.3% (vs. 71.5%, <0.001) in detecting flat malignant bladder lesions, which is significantly better than with the traditional OCT. Higher diagnostic efficacy of CP OCT in detecting early bladder cancer is associated with the ability to detect changes in epithelium and connective tissues.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jbio.201000088 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Influence of chlorhexidine dentin disinfection on universal adhesive performance: Interfacial adaptation and bond strength assessments.
PLoS One
December 2024
Departement of Restorative Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
Purpose: This study aimed to investigate the effect of chlorhexidine (CHX) cavity disinfectant on interfacial microleakage and micro-tensile bond strength (μTBS) of a universal adhesive bonded to dentin in both self-etch (SE) and etch-and-rinse (ER) modes.
Methods: Class I cavities were prepared in the coronal dentin of extracted human teeth and assigned to two etching modes (SE or ER), then subdivided by disinfection with or without CHX (n = 5). Cavities were restored using Single Bond Universal Adhesive and Filtek Z350 XT composite.
Layered Babinet complementary patterns acting as asymmetric negative index metamaterial.
Sci Rep
November 2024
Department of Optics and Quantum Electronics, University of Szeged, Dóm tér 9, Szeged, 6720, Hungary.
Azimuthal orientation and handedness dependence of the optical responses, accompanied by asymmetric transmission and asymmetric dichroism, were demonstrated on multilayers constructed with subwavelength periodic arrays of Babinet complementary miniarrays, illuminated by linearly and circularly polarized light. In case of single-sided illumination asymmetric optical responses were observed at the spectral location of maximal cross-polarization that is accompanied by radiative electric dipoles and weak, slowly-rotating in-plane magnetic dipoles on the nano-objects; where the outgoing waves are elliptically (almost circularly) polarized. The negative index material phenomenon was demonstrated, where the electric and magnetic dipoles overlap both spatially and spectrally.
View Article and Find Full Text PDFEnhanced Photocatalytic Degradation of Environmental Pollutants Using a Triphenylamine-Based Polymer: Synthesis, Characterization, and Mechanistic Insights.
Langmuir
December 2024
Department of Chemistry, Netaji Subhas University of Technology, Delhi 110078, India.
Conjugated porous organic polymers have sparked growing research attention as photocatalysts owing to their high surface area, tunable pores, and capacity to collect and transfer light energy via their delocalized backbone. However, the synthesis methods for preparing these polymers require difficult experimental setups, such as high polymerization temperature, inert atmosphere, and use of transition metal catalysts. In the present work, a triphenylamine-based conjugated porous polymer (TPA-BPA) has been synthesized employing tris(4-aminophenyl)amine (TPA) and biphenyldicarboxaldehyde (BPA) as precursors via a one-pot Schiff base reaction in ambient conditions in the absence of the metal catalyst.
View Article and Find Full Text PDFYtterbium (Yb)-doped materials are an excellent choice for efficient and powerful ultrafast lasers. They exhibit favorable emission properties, which include a low quantum defect and compatibility with cost-effective high-power pump diodes. While being strongly beneficial for efficiency, the low quantum defect is a challenge for operation in the few-cycle regime.
View Article and Find Full Text PDFImaging human coronary cholesterol/urate crystals with cross-polarized micro-optical coherence tomography.
Front Cardiovasc Med
October 2024
Wellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, Boston, MA, United States.
Introduction: Birefringent crystals such as monosodium-urate (MSU) and cholesterol crystals (CC) likely contribute to the progression of coronary artery disease (CAD) due to their potential to exacerbate inflammation through inflammatory cytokine activation. Here, we present cross-polarized micro-optical coherence tomography (CP-µOCT) for visualizing individual birefringent crystals in human coronary arteries.
Methods And Results: Human cadaver coronary arteries with a history of CAD with or without gout were dissected for CP-µOCT imaging.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!