Long-Standing Scirrhous Breast Carcinoma en Cuirasse.

BACKGROUND: The stromal reaction may be one of the key factors in the development of breast carcinomas. CASE REPORT: We report the case of an 80-year-old female patient who ignored a very slow growing, extensive scirrhous breast carcinoma for almost 20 years duration. RESULTS: Histopathology analysis revealed a Scarff Bloom Richardson (SBR)3-grade, estrogen receptor (ER)-positive (80%), progesterone receptor (PR)-positive (10%), HER2/neu-negative, lobular-invasive, scirrhous breast carcinoma with large cells. CONCLUSION: A strong peritumoral fibrous stromal reaction may explain the longstanding evolution of the tumor without any distant metastases.