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Clinical Manifestations.
Alzheimers Dement
December 2024
Memory and Aging Center, UCSF Weill Institute for Neurosciences, San Francisco, CA, USA.
Background: The ALLFTD (ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration) study is an NIH-funded effort to prepare for clinical trials in sporadic (s-FTLD) and familial (f-FTLD) FTLD syndromes by characterizing cohorts, developing new clinical trial outcome measures, and evaluating disease progression. To understand disease trajectories in the context of potential preventative or disease-modifying therapeutic agents, comprehensive evaluation across multiple time-points is crucial.
Method: ALLFTD evaluates participants with FTLD spectrum disorders (bvFTD, svPPA, nfvPPA, FTD-ALS, CBS, PSP), with strong family histories of FTLD, or known FTLD-associated genetic variants within the family.
Development and construction of a portable wind tunnel for investigating wind erosion through the application of photogrammetry techniques.
Sci Rep
January 2025
Department of Electrical Engineering, Faculty of Engineering, Razi University, Kermanshah, Iran.
Climate change is one of the most crucial issues in human society such that if it is not given sufficient attention, it can become a great threat to both humans and the Earth. Due to global warming, soil erosion is increasing in different regions. Therefore, this issue will require further investigation and the use of new tools.
View Article and Find Full Text PDFEco-reliable operation based on clean environmental condition for the grid-connected renewable energy hubs with heat pump and hydrogen, thermal and compressed air storage systems.
Sci Rep
January 2025
Department of Engineering, Islamic Azad University of Shahreza Branch, Shahreza, Iran.
Energy hubs, with their diverse regeneration and storage sources, can engage concurrently in energy transfer and storage. It is anticipated that managing the energy of these hubs within energy networks could enhance economic, environmental, and technical metrics. This article explains how electrical and thermal network hubs manage their energy consumption in the context of the multi-criteria objectives of efficiency, sustainability, reliability of the network operator, and operation.
View Article and Find Full Text PDFHyperspectral inversion of heavy metal content in farmland soil under conservation tillage of black soils.
Sci Rep
January 2025
College of Jilin Emergency Management, Changchun Institute of Technology, Changchun, 130012, China.
Globally, heavy metal (HM) soil pollution is becoming an increasingly serious concern. Heavy metals in soils pose significant environmental and health risks due to their persistence, toxicity, and potential for bioaccumulation. These metals often originate from anthropogenic activities such as industrial emissions, agricultural practices, and improper waste disposal.
View Article and Find Full Text PDFThe anticancer activity of fucoidan coated selenium nanoparticles and curcumin nanoparticles against colorectal cancer lines.
Sci Rep
January 2025
Department of Fish Processing and Biotechnology, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.
Cancers still globally endanger millions of people yearly; the incidences/mortalities of colorectal cancers are particularly increasing. The natural nanoparticles (NPs) and marine biopolymers were anticipated to provide effectual safe significances for managing cancers. The transformation of curcumin to nano-curcumin (NCur) was conducted with gum Arabic.
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