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Objectives: Assessment of gustatory function is a central part of the diagnosis of patients with chemosensory dysfunctions. The taste of monosodium glutamate was described as umami taste a century ago by Ikeda. The aim of this study was to extend a validated gustatory test with 4 concentrations of monosodium glutamate.
Methods: The investigation included 96 subjects who reported having a normal sense of taste and smell. Taste function was assessed by 4 concentrations of sweet, sour, salty, bitter, and umami tastes (extended version) and compared to results obtained in a control group (n = 139) not presented with umami. In a subgroup of 46 participants, the complete test was repeated within 7 days to obtain retest values.
Results: Group comparisons exhibited no differences in taste sensitivity for each of the 4 taste qualities (p > 0.3) and no deviation with regard to the sum of correctly identified tastants (p = 0.81). Test-retest data from the extended version revealed a high correlation of scores (r46 = 0.77; p < 0.001).
Conclusions: The results indicate that the extended version of the gustatory test is applicable for experimental and clinical settings.
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http://dx.doi.org/10.1177/000348941112000602 | DOI Listing |
Psychon Bull Rev
March 2025
Department of Psychology, University of Milano-Bicocca, Milan, Italy.
Semantic knowledge plays an active role in many well-known false memory phenomena, including those emerging from the Deese-Roediger-McDermott (DRM) task. Indeed, in this experimental paradigm, humans tend to falsely recognize newly presented words via activation of other previously shown stimuli. In the present study we aimed to test what happens in cases in which no apparent prior semantic knowledge is available, like in the case of entirely novel lexical stimuli.
View Article and Find Full Text PDFAppl Neuropsychol Adult
March 2025
Department of Speech Therapy, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Aim: Aphasia, primarily recognized as a language disorder following stroke, often is presented with concurrent emotional and social difficulties, including depression. This study investigated whether the type of aphasia-Broca's or subcortical-may be related to the prevalence of depression and overall quality of life (QOL) in affected individuals.
Methods: The present study involved 46 individuals with chronic aphasia resulting from left hemisphere strokes.
Drugs Real World Outcomes
March 2025
Department of Translational Biomedicine and Neurosciences (DiBraiN), Multiple Sclerosis Center - Policlinico of Bari, University of Bari "Aldo Moro", Bari, Italy.
Background And Objectives: Extended follow-up data from real-world cohorts of patients with multiple sclerosis treated with ocrelizumab (OCR) are becoming widely available. This monocentric retrospective study aimed to evaluate the long-term effectiveness of OCR and its impact on immunoglobulin (Ig) levels, lymphocyte subsets, and infections in a cohort of patients with relapsing remitting, primary progressive, and secondary progressive multiple sclerosis.
Methods: Patients followed at the Multiple Sclerosis Center of Bari with ≥ 2 years of OCR treatment were retrospectively recruited in 2024.
World J Urol
January 2025
Institute of Social Medicine and Health Systems Research, Otto-von-Guericke-University Magdeburg, Medical Faculty, Magdeburg, Germany.
Purpose: The Acute Cystitis Symptom Score (ACSS) is a clinically validated instrument to assess symptoms and quality of life in women with uncomplicated urinary tract infections (uUTIs). A previous study examining the content validity of the German version of the ACSS has shown some methodological limitations when rated against the criteria for content validity of the COnsensus-based Standards for the Selection of Health Measurement INstruments (COSMIN) initiative. Extending the existing evidence, the present study aimed to assess the content validity of the German version of the ACSS according to the criteria of the COSMIN methodology.
View Article and Find Full Text PDFJ Public Health Afr
February 2025
University of North Carolina Project, Charlotte, United States of America.
Background: The COVID-19 pandemic led to an urgent need for a global vaccine. Despite being a priority group, the vaccine uptake among healthcare workers (HCWs) remains low.
Aim: This article assessed the COVID-19 vaccine uptake and its associated barriers in Malawi.
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