AI Article Synopsis
- - The study examined the epidemiological features of paralytic cases related to type 2 vaccine-derived poliovirus (VDPV) in Zhaotong city, China, in 2010, focusing on the excretion status of affected individuals and healthy children under five.
- - Researchers collected 108 stool samples (from a case, close contacts, and healthy children) but found no evidence of VDPV or related strains circulating among these groups.
- - They isolated 21 non-polio enteroviruses (NPEVs) from 105 samples, with 52.4% being HEV-A and 47.6% HEV-B, indicating the presence of other enterovirus infections in the area.
Article Abstract
To find out epidemiological feature of paralytic cases caused by type 2 vaccine-derived poliovirus (VDPV) and the excretion status of the case and to explore the enterovirus infection status among healthy children under five years old around the case in Zhaotong city, Yunnan Province in 2010. Field epidemiological studies at the epidemic area were conducted and a total of 108 stool samples were collected, three from the case, seven from the close contacts and 98 from the healthy children. VDPV was not isolated again from the case; Sabin-like PV strains or VDPV were not isolated from the close contacts and the healthy children; An active search for acute flaccid paralysis cases was conducted in the area, which indicated that the VDPV did not cause virus circulation in local area. Twenty one (20.0%) NPEVs were isolated from 105 stool samples. Among the 21 NPEV isolates, 11 isolates (52.4%) were HEV-A (3 serotypes), 10 isolates (47.6%) were HEV-B (4 serotypes).
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