DNA confined to rigid nanotubes shows density fluctuations around its stretched equilibrium conformation. We report an experimental investigation of the length-scale dependent dynamics of these density fluctuations. We find that for highly elongated molecules a Rouse description is consistent with observations at sufficiently large length scales. We further find that for strongly fluctuating molecules, or short length scales, such Rouse modes cannot be detected due to strong mixing of fluctuation modes.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138799PMC
http://dx.doi.org/10.1063/1.3602922DOI Listing

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