Expedited Baeyer-Villiger oxidation of steroidal ketones by microwave irradiation.

Steroids

Natural Products Chemistry Division, North East Institute of Science & Technology, CSIR, Jorhat 785 006, India.

Published: November 2011

Microwave (MW) assisted reactions are currently having considerable importance in the synthesis of organic compounds. Considering the remarkable application of Baeyer-Villiger (BV) reaction in the synthesis of natural products and steroid-peptide conjugates, we report here some of our findings of BV oxidation of carbonyl compounds with special reference to steroidal ketones under MW irradiation justifying its accelerating effect.

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http://dx.doi.org/10.1016/j.steroids.2011.06.014DOI Listing

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