Intraocular T-cell lymphoma due to mycosis fungoides and response to intravitreal methotrexate.

Ocul Immunol Inflamm

Department of Ophthalmology, Vanderbilt University, Nashville, Tennessee 37232, USA.

Published: August 2011

Purpose: To report a case of mycosis fungoides with subsequent intraocular involvement and good response to intravitreal methotrexate.

Design: Case report.

Methods: Retrospective chart review.

Results: This is a rare case of intraocular T-cell lymphoma due to mycosis fungoides, which responded to intravitreal methotrexate therapy in a previous vitrectomized eye.

Conclusions: Intraocular T-cell lymphoma is a rare manifestation of mycosis fungoides and should be considered in the differential diagnosis of chronic uveitis in patients with this history. Intravitreal methotrexate may be an effective adjunctive treatment for this condition.

Download full-text PDF

Source
http://dx.doi.org/10.3109/09273948.2011.563896DOI Listing

Publication Analysis

Top Keywords

mycosis fungoides
16
intraocular t-cell
12
t-cell lymphoma
12
intravitreal methotrexate
12
lymphoma mycosis
8
response intravitreal
8
intraocular
4
mycosis
4
fungoides
4
fungoides response
4

Similar Publications

Objective: To highlight the importance of early recognition of hypopigmented mycosis fungoides (HMF) in cases of cutaneous hypochromia in children, with a view to an effective diagnostic and therapeutic approach.

Case Description: Two cases of HMF in children are reported. The first case involves an eight-year-old boy with hypochromic macules on the trunk and root of the upper and lower limbs, while the second case is a six-year-old boy with widespread hypochromic patches.

View Article and Find Full Text PDF

Background And Objectives: Patients with cutaneous lymphomas (CL) are at an increased risk of developing secondary malignancies. This study aimed to assess the frequency of association between CL and Kaposi sarcoma (KS) and to identify factors that may promote the co-occurrence of these two diseases.

Patients And Methods: On January 25, 2024, we conducted a systematic search of four electronic medical databases to identify all published cases of KS associated with CL.

View Article and Find Full Text PDF

Ultra-high-frequency Ultrasound in the Objective Assessment of Chlormethine Gel Efficacy: A Case Report.

Acta Dermatovenerol Croat

November 2024

Agata Janowska, MD, Department of Dermatology, , University of Pisa, Via Roma 67, 56126, Pisa, Italy; Phone: +39 050 992436, Fax: +39 050 992556,

Mycosis fungoides (MF) represent the most frequent form of cutaneous T-cell lymphoma (CTCL). Chlormethine gel has been approved as first-line therapy in MF. The classification of early forms of MF is clinically and histologically complex even for experienced clinicians.

View Article and Find Full Text PDF
Article Synopsis
  • Cutaneous T cell lymphomas (CTCLs) are challenging to treat non-Hodgkin lymphomas, with Mycosis fungoides (MF) and Sezary syndrome (SS) being the most prevalent subtypes.
  • There is no established standard treatment or cure for these conditions, making management difficult.
  • Recent clinical trials are testing new therapies, including innovative chemotherapies, antibodies, immunotherapies, and cellular therapies that could enhance treatment options for MF and SS.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!