AI Article Synopsis
- A 77-year-old woman developed endophthalmitis (eye infection) after surgery, showing severe reaction in her eye.
- She underwent procedures to sample the eye fluid, which tested positive for Mycobacterium tuberculosis (MTB), even though there were no signs of infection elsewhere in her body.
- After treatment with antibiotics and antitubercular drugs, her vision improved significantly by the one-month follow-up.
Article Abstract
Purpose: To report a case of endophthalmitis caused by Mycobacterium tuberculosis (MTB).
Design: Descriptive case report.
Methods: Review of patient records.
Results: A 77-year-old female patient presented with postoperative endophthalmitis. Anterior segment examination revealed a severe anterior chamber and vitreous reaction. She underwent an anterior chamber tap followed by a vitrectomy, which were both positive for MTB via polymerase chain reaction. There was no radiological evidence of systemic disease. She responded well to antibiotics and antitubercular therapy for a final visual acuity of 6/9 at 1-month follow-up.
Conclusions: Mycobacterium tuberculosis may be an etiologic agent for postoperative endophthalmitis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/09273948.2011.562342 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Executive Summary: Clinical Practice Guidelines on the Management of Resistant Tuberculosis of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) and the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC).
Arch Bronconeumol
December 2024
Pulmonology Service, Cruces University Hospital (OSI EEC), Barakaldo, Spain; BioBizkaia Health Research Institute, Spain.
The Spanish Society of Pneumology and Thoracic Surgery (SEPAR) and the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) have developed together Clinical Practice Guidelines (GPC) on the management of people affected by tuberculosis (TB) resistant to drugs with activity against Mycobacterium tuberculosis. These clinical practice guidelines include the latest updates of the SEPAR regulations for the diagnosis and treatment of drug-resistant TB from 2017 and 2020 as the starting point. The methodology included asking relevant clinical questions based on PICO methodology, a literature search focusing on each question, and a systematic and comprehensive evaluation of the evidence, with a summary of this evidence for each question.
View Article and Find Full Text PDFGlobally, drug-resistant tuberculosis (DR-TB) is responsible for 13% of mortality attributable to antimicrobial resistance. In Ethiopia, extrapulmonary tuberculosis (EPTB) is a significant public health challenge, and drug resistance (DR) in EPTB is often overlooked. In a cross-sectional study conducted between August 2022 and October 2023, we aimed to explore the magnitude of phenotypic drug resistance and identify genetic mutations linked to resistance using 189 Mycobacterium tuberculosis (MTB) isolates cultured from extrapulmonary clinical specimens.
View Article and Find Full Text PDFUnlabelled: Crosstalk between autophagy, host cell death, and inflammatory host responses to bacterial pathogens enables effective innate immune responses that limit bacterial growth while minimizing coincidental host damage. ( ) thwarts innate immune defense mechanisms in alveolar macrophages (AMs) during the initial stages of infection and in recruited bone marrow-derived cells during later stages of infection. However, how protective inflammatory responses are achieved during infection and the variation of the response in different macrophage subtypes remain obscure.
View Article and Find Full Text PDFUnlabelled: Mycobacterial cell envelopes are rich in unusual lipids and glycans that play key roles during infection and vaccination. The most abundant envelope glycolipid is trehalose dimycolate (TDM). TDM compromises the host response to mycobacterial species via multiple mechanisms, including inhibition of phagosome maturation.
View Article and Find Full Text PDFPathogen sequencing is an important tool for disease surveillance and demonstrated its high value during the COVID-19 pandemic. Viral sequencing during the pandemic allowed us to track disease spread, quickly identify new variants, and guide the development of vaccines. Tiled amplicon sequencing, in which a panel of primers is used for multiplex amplification of fragments across an entire genome, was the cornerstone of SARS-CoV-2 sequencing.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!