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Mandatory Requirements for Planning and Commissioning of Medical Cyclotron Facility.
Indian J Nucl Med
November 2024
Health Physics Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.
Over the last 15 years, there has been substantial growth in the installation of medical cyclotrons. This is mainly due to the increased demand for the production of positron emission tomography radiopharmaceuticals. In every country, there is a regulatory body that regulates the uses of medical cyclotron intending to protect occupational workers, the public, and the environment.
View Article and Find Full Text PDFDigital light processing printing of non-modified protein-only compositions.
Mater Today Bio
February 2025
Institute of Chemistry and Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, 9190401, Israel.
This study explores the utilization of digital light processing (DLP) printing to fabricate complex structures using native gelatin as the sole structural component for applications in biological implants. Unlike approaches relying on synthetic materials or chemically modified biopolymers, this research harnesses the inherent properties of gelatin to create biocompatible structures. The printing process is based on a crosslinking mechanism using a di-tyrosine formation initiated by visible light irradiation.
View Article and Find Full Text PDFFruit Cuticle Thickness and Anatomical Changes in Pedicel Xylem Vessels Influence Fruit Transpiration and Calcium Accumulation in Cranberry Fruit.
Physiol Plant
January 2025
Department of Plant and Agroecosystem Sciences, University of Wisconsin-Madison, Madison, WI.
Ca is a key nutrient for fruit quality due to its role in bonding with pectin in the cell wall, providing strength through cell-to-cell adhesion, thus increasing fruit firmness and extending post-harvest life. However, Ca accumulation is mostly limited to the initial stages of fruit development due to anatomical and physiological changes that occur as fruits develop. The objective of this study was to evaluate fruit transpiration, cuticle thickness, and pedicel vessel changes during cranberry fruit development and the effect these parameters might have on Ca translocation.
View Article and Find Full Text PDFA phase Ia study of a novel anti-HER2 antibody-drug conjugate GQ1001 in patients with previously treated HER2 positive advanced solid tumors.
J Transl Med
January 2025
Scientia Clinical Research and Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, 2052, Australia.
Background: A novel anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC) GQ1001 was assessed in patients with previously treated HER2 positive advanced solid tumors in a global multi-center phase Ia dose escalation trial.
Methods: In this phase Ia trial, a modified 3 + 3 study design was adopted during dose escalation phase. Eligible patients were enrolled, and GQ1001 monotherapy was administered intravenously every 3 weeks.
Balancing the solar irradiance needs: optimising growth in sphagnum palustre through tailored UV-B effects.
BMC Plant Biol
January 2025
Hubei Key Laboratory of Biological Resource Protection and Utilization, Enshi, 445000, China.
Background: The carbon sequestration potential and water retention capacity of peatlands are closely linked to the growth dynamics of Sphagnum mosses. However, few studies have focused on the response of Sphagnum moss growth dynamics to UV-B radiation, and existing research has emphasized species differences. In this study, Sphagnum palustre L.
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