AI Article Synopsis
- The study aimed to identify risk factors for contrast-induced nephropathy (CIN) in patients undergoing coronary interventional therapy (PCI) and evaluate its clinical impact and prevention strategies.
- CIN was notably linked to pre-existing chronic renal failure, diabetes, and the use of large doses of contrast during the procedure.
- Patients who developed CIN faced higher rates of cardiac mortality, myocardial infarction, and major adverse cardiac events within one year post-PCI, highlighting the need for careful preoperative management to prevent CIN.
Article Abstract
Objective: To identify the risk factors of contrast-induced nephropathy (CIN) after coronary interventional therapy (PCI) in patients with coronary heart disease and analyze the clinical outcomes and the preventive measures of CIN.
Methods: Ninety-one patients who developed CIN after PCI were retrospectively analyzed to identify the risk factors and explore the preventive measures.
Results: CIN was strongly associated with pre-procedural chronic renal failure, diabetes mellitus and administration of large-dose contrast. The incidence of cardiac mortality in hospital or in the follow-up at one year after PCI, and the incidence of myocardial infarction or major adverse cardiac events in the follow-up at one year were obviously higher in patients with CIN than those without CIN.
Conclusion: Chronic renal failure, diabetes mellitus and large-dose contrast administration are 3 independent risk factors of CIN, which affects the prognosis of the patients. Reinforcement of a comprehensive perioperative management of PCI, especially a rigorous preoperative preparation, can be an important strategy for prevention of CIN.
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