AI Article Synopsis
- The paper presents a compact, head-mountable CMOS camera designed for monitoring rapid neuronal activity in freely moving rodents using fluorescent indicators.
- It can detect minute changes in light intensity at an impressive frame rate of 500 frames per second, with technical specifications including a resolution of 32×32 and a sensitivity of 0.62V/lxs.
- This innovative camera features built-in intensity offset subtraction circuitry and is part of a miniaturized epi-fluorescent microscope, marking it as a pioneering tool in mobile, scientific-grade physiology imaging.
Article Abstract
We report a head-mountable CMOS camera for recording rapid neuronal activity in freely moving rodents using fluorescent activity reporters. This small, lightweight camera is capable of detecting small changes in light intensity (0.2% ΔI/I) at 500fps. The camera has a resolution of 32×32, sensitivity of 0.62V/lxs, conversion gain of 0.52μV/e(-) and well capacity of 2.1Me(-). The camera, containing intensity offset subtraction circuitry within the imaging chip, is part of a miniaturized epi-fluorescent microscope and represents a first generation, mobile scientific-grade, physiology imaging camera.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179772 | PMC |
| http://dx.doi.org/10.1016/j.jneumeth.2011.06.024 | DOI Listing |
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