AI Article Synopsis
- Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, primarily affects lymph nodes and can also involve other sites, including the breast.
- A unique case was reported where a patient had a breast mass and swollen axillary lymph nodes that initially appeared to be cancerous both clinically and through imaging.
- Although initial biopsies suggested lymphoma, a later excisional biopsy confirmed Rosai-Dorfman disease; the condition recurred multiple times in different locations within a year.
Article Abstract
Rosai-Dorfman disease (also called sinus histiocytosis with massive lymphadenopathy) involves lymph nodes or lymph nodes with extranodal sites. We present a unique case of a patient presenting with a breast mass and axillary lymphadenopathy, mimicking malignancy clinically and radiographically. Core needle biopsies of the breast and axillary lymph node showed histologic features concerning the lymphoma. However, excisional biopsy specimen demonstrated characteristic features of Rosai-Dorfman disease. The disease recurred locally 6 months later in the same breast, 1 month later in the contralateral breast, and 11 month later in the subcutaneous tissue of left flank. A review of the literature of Rosai-Dorfman disease involving the breast is also presented.
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| http://dx.doi.org/10.1111/j.1524-4741.2011.01131.x | DOI Listing |
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