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Effects of physical exercise on cardio-respiratory health of young adults during short-term exposure to varying air pollution levels.
BMC Public Health
December 2024
School of Exercise and Health, Shanghai University of Sport, Yangpu District Qingyuan Huan Road 650, Shanghai, 200438, China.
Background: Air pollution (AP) has become a substantial environmental issue affecting human cardiorespiratory health. Physical exercise (PE) is widely accepted to promote cardiorespiratory health. There is a paucity of research on the point at which the level of polluted environment engaged in PE could be used as a preventive approach to compensate for the damages of AP.
View Article and Find Full Text PDFEffects of a Circuit Training Program on Myokine Levels in Insulin-Resistant Women: A Randomised Controlled Trial.
J Diabetes Res
December 2024
Department of Medical Biology, Poznan University of Physical Education 61-871, Poznan, Poland.
Circuit training is a form of body conditioning with endurance and resistance components. Given the function of skeletal muscle as an endocrine organ secreting various myokines involved in maintaining glucose metabolism homeostasis, our study focused on estimating the impact of the implemented training program on the direction of changes in myokines such as interleukin (IL)-6, IL-10, fibroblast growth factor 21 (FGF21), and irisin in women newly diagnosed with insulin resistance. This prospective controlled trial randomly divided 42 women into two groups.
View Article and Find Full Text PDFEffects of Repeated Exposure to Ambient Cold on the Development of Inflammatory Pain in a Rat Model of Knee Arthritis.
Life (Basel)
November 2024
Department of Korean Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
This study investigated the effects of ambient cold exposure on inflammatory pain development, synovial cytokine levels, and spinal cord glial cell activation. Male Sprague-Dawley rats (6 weeks old) were divided into Cold and RT groups. The Cold group was exposed to cold (4 ± 1 °C) for 6 h/day for 5 consecutive days, while the RT group remained at room temperature (22 ± 1 °C).
View Article and Find Full Text PDFA Prospective Cohort Study on the Effects of Repeated Acute Stress on Cortisol Awakening Response and Immune Function in Military Medical Students.
Biomedicines
November 2024
Department of Biomedical Sciences, College of Osteopathic Medicine, Rocky Vista University, 8401 S Chambers Rd, Englewood, CO 80112, USA.
Article Synopsis
- * Results showed a significant drop in the CAR on the third day, with recovery observed on the fourth day, and specific cytokines (like IL-6 and CXCL1) were found to correlate with these cortisol patterns.
- * The findings suggest that the CAR may reflect psychological burnout and highlight how stress affects immune function, offering insights for managing stress in high-pressure professions like military and medical fields.
Administration of monophosphoryl lipid A shortly after traumatic brain injury blocks the following spatial and avoidance memory loss and neuroinflammation.
Sci Rep
November 2024
Department of Physiology and Pharmacology, Pasteur Institute of Iran, Tehran, Iran.
Traumatic brain injury (TBI) frequently leads to cognitive impairments. The toll-like receptor 4 (TLR4) ligand, Monophosphoryl lipid A (MPL), has shown promise in modulating neuroinflammatory responses after TBI. We investigated the effects of MPL on spatial memory, passive avoidance memory, neuronal survival, and inflammatory/anti-inflammatory cytokines in rat brain following mild-to-moderate TBI.
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