Forty cases of irritable bowel syndrome with complete dietary histories were examined retrospectively. Included were infants and children aged 6 to 42 months, who had diarrhoea at least 4 weeks duration, a normal pattern of growth and no evidence of malabsorption or enteric infections. The majority (92.5%) of these patients had been on high carbohydrate, high protein and low fat diets prior to referral. Ten percent of the patients lost weight as a result of marginal caloric intake subsequent to restrictive dietary advice. In 19 of the 25 patients compliant to dietary recommendations, this modification was associated with the resolution of symptoms. Based on this study and previous others we suggest to carefully gather dietary intake information for all patients fulfilling the usual criteria for irritable bowel syndrome and recommend a therapeutic trial of increased dietary fat and diminished carbohydrates and even proteins intake.
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Adv Clin Exp Med
January 2025
specialist, Oral and Maxillofacial Surgery, Guwahati, India.
Background: Vitamin D supplementation could offer irritable bowel syndrome (IBS) patients significant improvements in terms of symptom severity and overall quality of life (QoL). Yet, the potential benefits and risks associated with vitamin D supplementation still require additional investigation.
Objectives: We aimed to evaluate the impact of vitamin D supplementation on IBS using a systematic review and meta-analysis.
J Gastroenterol Hepatol
January 2025
Faculty of Medicine, Division of Gastroenterology, Department of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Background: Gas production due to fermentation from fructose malabsorption (FM) or lactose malabsorption (LM) and small intestinal bacterial overgrowth (SIBO) contribute to the development of gastrointestinal symptoms in patients with irritable bowel syndrome (IBS). However, the impact of the carbohydrate malabsorption, unlike SIBO, is relatively unknown.
Methodology: A multicenter, prospective study of consecutive adults with IBS who underwent a hydrogen breath test (HBT) (glucose, 75 g; lactose, 25 g; or fructose, 25 g) was conducted.
Acta Parasitol
January 2025
Department of Animal Biology, Faculty of Science, Damascus University, Damascus, Syria.
Purpose: Blastocystis sp. is a common enteric human parasite, which recently has been linked to gastrointestinal disorders i.e.
View Article and Find Full Text PDFScand J Gastroenterol
January 2025
Department of Gastroenterology, Hepatology, and Nutrition, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Background: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder seen by both primary care providers (PCPs) and gastroenterologists, and further diagnostic testing is generally discouraged unless red-flag symptoms are present.
Aims: Examine if advanced serologic testing for chronic abdominal pain in IBS patients followed society-specific guidelines and evaluate the diagnostic accuracy of these tests.
Methods: The study involved a retrospective cross-sectional analysis of adults aged 18 and older who were seen at our institution between 2013 and 2018.
Front Allergy
January 2025
Department of Medicine and Surgery, Pediatric Unit, University of Perugia, Perugia, Italy.
The gut barrier encompasses several interactive, physical, and functional components, such as the gut microbiota, the mucus layer, the epithelial layer and the gut mucosal immunity. All these contribute to homeostasis in a well-regulated manner. Nevertheless, this frail balance might be disrupted for instance by westernized dietary habits, infections, pollution or exposure to antibiotics, thus diminishing protective immunity and leading to the onset of chronic diseases.
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