2-[(4-Chloro-phen-yl)(hy-droxy)meth-yl]-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.

Acta Crystallogr Sect E Struct Rep Online

Key Laboratory of Pesticide and Chemical Biology, College of Chemistry, Central China Normal University, Wuhan 430079, People's Republic of China .

Published: April 2011

In the title compound, C(12)H(16)ClO(4)P, the phospho-nate ring adopts a chair conformation. In the crystal, intermolecular O-H⋯O hydrogen bonds link the molecules into chains propagating along the b axis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099943PMC
http://dx.doi.org/10.1107/S1600536811008944DOI Listing

Publication Analysis

Top Keywords

2-[4-chloro-phen-ylhy-droxymeth-yl]-55-dimethyl-132-dioxaphosphinan-2-one title
4
title compound
4
compound c12h16clo4p
4
c12h16clo4p phospho-nate
4
phospho-nate ring
4
ring adopts
4
adopts chair
4
chair conformation
4
conformation crystal
4
crystal intermolecular
4

Similar Publications

Background: The aging global population and the rising prevalence of chronic disease and multimorbidity have strained health care systems, driving the need for expanded health care resources. Transitioning to home-based care (HBC) may offer a sustainable solution, supported by technological innovations such as Internet of Medical Things (IoMT) platforms. However, the full potential of IoMT platforms to streamline health care delivery is often limited by interoperability challenges that hinder communication and pose risks to patient safety.

View Article and Find Full Text PDF

Five previously unreported 5-hydroxymethylfurfural (5-HMF) derivatives, including chinenfurfurals A () and B () as 5-HMF-citric acid hybrids and chinenfurfurals C-E (-) as 5-HMF oligomers, as well as four known analogues (-), were isolated from the fruits of a well-known Chinese herbal species . The structures of these furfural compounds were established by detailed analyses of spectroscopic data especially HRMS and NMR, and it is the first report of furfural type constituents from the title species. The anti-inflammatory property of them was further evaluated by testing their inhibition against the production of nitric oxide in lipopolysaccharide-activated murine RAW264.

View Article and Find Full Text PDF

Purpose: The purpose of this review study is to investigate the effect of curcumin on the phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway in various diseases. Curcumin, the main compound found in turmeric, has attracted a lot of attention for its diverse pharmacological properties. These properties have increased the therapeutic potential of curcumin in chronic diseases such as cardiovascular disease, Type 2 diabetes, obesity, non-alcoholic fatty liver disease, kidney disease, and neurodegenerative diseases.

View Article and Find Full Text PDF

Objective: Thyroid dysfunction represents common disorder occurring very frequently among women of reproductive age, including pregnancy. The aim of this literature review was to determine in which way thyroid function during pregnancy is associated with GDM.

Design: We conducted review of the literature following the basic principles of literature search.

View Article and Find Full Text PDF

Objective: The objective of this systematic review was to identify, critically appraise, and synthesize the best available qualitative evidence on parent and carer experiences of communications by health care professionals (HCPs) concerning children's higher weight.

Introduction: A child's higher weight can be a sensitive issue to discuss in health care, but successful communication with parents can increase parental compliance with treatment and improve overall family welfare. Public discourse on obesity has shifted in recent years and created pressure to change the way that weight is discussed in health care.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!