We screened 735 HIV-infected patients in Switzerland with unexplained alanine aminotransferase elevation for hepatitis E virus (HEV) immunoglobulin G. Although HEV seroprevalence in this population is low (2.6%), HEV RNA can persist in patients with low CD4 cell counts. Findings suggest chronic HEV infection should be considered as a cause of persistent alanine aminotransferase elevation.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358194PMC
http://dx.doi.org/10.3201/eid/1706.101067DOI Listing

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