Giant congenital melanocytic nevi (GCMN) are rare lesions that are present in 1 in every 20,000 new births. A 10-year review of all patients treated at a pediatric burn center was performed with the goal of identifying the characteristics of patients with GCMN and the outcomes of the treatment provided in a burn center. Thirty-six patients met the definition of GCMN; 64% were female and 36% were male. The most common ethnicity was white (47%), followed by Latino (19%). Most patients were between the ages of 1 and 10 years at the time of their first procedure (64%), and the mean age of patients at the time of their first procedure was 7 years. Eighty-nine percent had only one lesion. The most common location of lesions was the face (64%), followed by the scalp (17%) and back (17%). Seventy-four percent of the samples sent to pathology were congenital compound melanocytic nevi, and 20% were congenital intradermal melanocytic nevi. None of the lesions contained malignant changes at the time of the pathological examination. The various treatment modalities provided in the burn unit are reviewed. The authors conclude that the burn unit is an ideal setting for the treatment of GCMN.
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http://dx.doi.org/10.1097/BCR.0b013e3182223c58 | DOI Listing |
Unlabelled: Considering the similarity in clinical presentations of iris neoplasms of various origins, questions of their noninvasive diagnosis remain relevant. Optical coherence tomography angiography (OCT-A) is one of the imaging method that enables visualization of tumor vessels.
Purpose: This article examines the features of angioarchitecture, vascular network density, and perfusion density of iris melanoma and progressive iris nevus using OCT-A.
Diagn Pathol
December 2024
Department of Pathology, Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, 210042, China.
Background: Isolated immunohistochemical indicators are limited to diagnose melanocytic neoplasms. This retrospective study is to assess the diagnostic value of combined immunohistochemical analysis targeting preferentially expressed antigen in melanoma (PRAME) and p16 in melanocytic neoplasms, with a detailed focus on arcal lesions.
Methods: This was a single center cohort study from January 2022 to June 2023.
Georgian Med News
October 2024
European University, Department of Dermatology, Tbilisi, Georgia.
Unlabelled: Nevi developed in children are one of the topical issues of pediatric dermatology. The constant change in size and shape often worries parents, and unnecessary removal of the nevi is planned. The development of accompanying scars and sometimes recurring nevi presents a new problem for parents and dermatologists.
View Article and Find Full Text PDFClin Cosmet Investig Dermatol
December 2024
Department of Dermatology, Peking University People's Hospital, Beijing, People's Republic of China.
Purpose: The purpose of the study was to determine the efficacy of secondary intention healing of wounds after penile nevi surgical shave excision.
Patients And Methods: A retrospective study in the Department of Dermatology, Peking University People's Hospital, between 2019 and 2023, on 8 patients with penile nevi was performed. Patients were treated by surgical shave excision and underwent secondary intention healing.
Background And Aims: Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients.
Methods: This descriptive, retrospective study involved reviewing the records of patients diagnosed with Spitz nevus at a referral and academic hospital in Iran between 2016 and 2021.
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