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Prognostication: A fading Hippocratic art?
Explore (NY)
November 2024
Departments of Anesthesiology and Surgery, The University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, United States. Electronic address:
Over the past 75 years modern medicine has advanced in its ability to diagnose and treat many diseases. However, the medical profession's ability to prognosticate the course and outcome of an illness has not satisfied the needs of many patients. Physicians must not lose the ability, or desire, to consider the whole person in relation to a patient's disease.
View Article and Find Full Text PDFWhen DNA Mutations Interplay with Cellular Proliferation: A Narrative History of Theories of Carcinogenesis.
Cancers (Basel)
May 2024
Inserm U1296 Unit, "Radiation: Defense, Health and Environment", 28 Rue Laennec, 69008 Lyon, France.
While cancer is one of the most documented diseases, how normal cells become cancerous is still debated. To address this question, in the first part of this review, we investigated the long succession of theories of carcinogenesis since antiquity. Initiated by Hippocrates, Aristotle, and Galen, the humoral theory interpreted cancer as an excess of acid, the black bile.
View Article and Find Full Text PDFVascular Access in Percutaneous Coronary Intervention of Chronic Total Occlusions: A State-of-the-Art Review.
Circ Cardiovasc Interv
August 2023
Department of Cardiology, Isala Heart Center, Zwolle, the Netherlands (T.A.M., M.A.H.v.L.).
Article Synopsis
- Outcomes for chronic total occlusion percutaneous coronary intervention (PCI) have significantly improved over the past ten years, with a focus on enhancing safety during procedures.
- Vascular access site bleeding is a common complication that can occur during these procedures.
- The review discusses various strategies that have been developed to minimize vascular access site complications in chronic total occlusion PCI.
Clinical Reasoning in Cardiology: Past, Present and Future.
Arq Bras Cardiol
September 2022
Universidade Federal Fluminense - Hospital Universitário Antônio Pedro, Niterói , RJ - Brasil.
Clinical reasoning was born 2,500 years ago with Hippocrates, having evolved over the centuries, becoming a mixture of art and science. Several personalities throughout history have contributed to improving diagnostic accuracy. Nonetheless, diagnostic error is still common and causes a severe impact on healthcare systems.
View Article and Find Full Text PDFCauses, Angiographic Characteristics, and Management of Premature Myocardial Infarction: JACC State-of-the-Art Review.
J Am Coll Cardiol
June 2022
Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Among patients presenting with acute myocardial infarction (AMI), the proportion of young individuals has increased in recent years. Although coronary atherosclerosis is less extensive in young patients with AMI, with higher prevalence of single-vessel disease and rare left main involvement, the long-term prognosis is not benign. Young patients with AMI with obstructive coronary artery disease have similar risk factors as older patients except for higher prevalence of smoking, lipid disorders, and family history of premature coronary artery disease, and lower prevalence of diabetes mellitus and hypertension.
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